DEFB121 and NECTIN4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

		DEFB121	NECTIN4
Description		defensin beta 121	nectin cell adhesion molecule 4
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Plasma Membrane Adherens Junction Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding	Virus Receptor Activity Protein Binding Identical Protein Binding
	Biological Process	Defense Response To Bacterium Innate Immune Response	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Viral Entry Into Host Cell
Pathways		Beta defensins Defensins	Adherens junctions interactions Nectin/Necl trans heterodimerization
Drugs			Enfortumab vedotin
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) Prudent dietary pattern ( 28644415)
Interacting Genes		10 interacting genes: CD40 CLEC2D FAM209A GJA8 IL27RA LAYN LRRC25 NECTIN4 SSMEM1 SYNE4	6 interacting genes: AFDN DEFB121 NECTIN1 NECTIN2 PICK1 TIGIT
Entrez ID		245934	81607
HPRD ID		16791	17934
Ensembl ID		ENSG00000204548	ENSG00000143217
Uniprot IDs		A0A384MDM0 Q5GRF9 Q5J5C9	K4PZ75 Q96NY8
PDB IDs			4FRW 4GJT 4JJH
Enriched GO Terms of Interacting Partners?
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