DEFB121 and SYNE4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

		DEFB121	SYNE4
Description		defensin beta 121	spectrin repeat containing nuclear envelope family member 4
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Integral Component Of Nuclear Outer Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex
	Molecular Function	Molecular_function Protein Binding	Protein Binding
	Biological Process	Defense Response To Bacterium Innate Immune Response	Establishment Of Epithelial Cell Apical/basal Polarity
Pathways		Beta defensins Defensins
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) Prudent dietary pattern ( 28644415)
Interacting Genes		10 interacting genes: CD40 CLEC2D FAM209A GJA8 IL27RA LAYN LRRC25 NECTIN4 SSMEM1 SYNE4	57 interacting genes: ABT1 ADIPOQ BRICD5 C3orf52 CD47 CEP19 CLDN19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FAM241B FATE1 GADD45A GSK3B IGFBP5 ITM2B KLHL12 KLRG1 KTN1 MALL MARCHF2 NAGK OCLN OLFM4 OSTCP1 PAQR5 PLPP6 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TCEA2 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B WDR62 ZNF250 ZNF648
Entrez ID		245934	163183
HPRD ID		16791	08776
Ensembl ID		ENSG00000204548	ENSG00000181392
Uniprot IDs		A0A384MDM0 Q5GRF9 Q5J5C9	Q8N205
PDB IDs			6R16 6WMD
Enriched GO Terms of Interacting Partners?
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