SGK3 and SLC9A3R2

Number of citations of the paper that reports this interaction (PubMedID 11751930)
54

Data Source:
HPRD (in vitro)

		SGK3	SLC9A3R2
Description		serum/glucocorticoid regulated kinase family member 3	SLC9A3 regulator 2
Image
GO Annotations	Cellular Component	Nucleoplasm Early Endosome Cytosol Intracellular Membrane-bounded Organelle Recycling Endosome	Nucleus Plasma Membrane Focal Adhesion Endomembrane System Apical Plasma Membrane Extracellular Exosome
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Calcium Channel Regulator Activity Protein Binding ATP Binding Potassium Channel Regulator Activity Sodium Channel Regulator Activity Chloride Channel Regulator Activity Phosphatidylinositol Binding Protein Serine Kinase Activity	Signaling Receptor Binding Protein Binding Beta-catenin Binding Protein C-terminus Binding Phosphatase Binding Type 2 Metabotropic Glutamate Receptor Binding Type 3 Metabotropic Glutamate Receptor Binding Identical Protein Binding Protein-membrane Adaptor Activity Cadherin Binding
	Biological Process	Regulation Of Cell Growth Protein Phosphorylation Peptidyl-serine Phosphorylation Regulation Of Cell Migration Intracellular Signal Transduction Regulation Of Cell Population Proliferation Regulation Of DNA-binding Transcription Factor Activity	Protein-containing Complex Assembly Protein Localization To Plasma Membrane
Pathways		Stimuli-sensing channels
Drugs		Fostamatinib
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)	Diastolic blood pressure ( 27841878 30578418) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) Platelet distribution width ( 32888494) Pulse pressure ( 30578418) Red blood cell count ( 32888494) Reticulocyte count ( 32888494) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		8 interacting genes: APP GSK3A GSK3B ITCH LYN PDPK1 SLC9A3R2 SMCO1	43 interacting genes: ABCC4 ACE2 ACTN4 ADORA2B ADRB2 ATP2B2 CFTR DLGAP4 EZR IFT140 KCNJ1 LPAR1 LPAR2 P2RY1 PDGFRB PDPK1 PDZK1 PLCB3 PODXL PRKACA PRKCA PTEN PTH1R RDX RPS6KA1 SGK1 SGK3 SIAH1 SLC13A1 SLC22A4 SLC22A5 SLC22A9 SLC26A3 SLC34A1 SLC9A3 SLCO1A2 SLCO3A1 SRY TAFAZZIN TBC1D10A TRAF4 WWP2 WWTR1
Entrez ID		23678	9351
HPRD ID		06349	05946
Ensembl ID		ENSG00000104205	ENSG00000065054
Uniprot IDs		A0A024R807 Q53EW6 Q5H9Q5 Q96BR1	Q15599
PDB IDs		6EDX	2D11 2HE4 2OCS 4P0C
Enriched GO Terms of Interacting Partners?
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