FOLH1 and C3orf52

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FOLH1	C3orf52
Description		folate hydrolase 1	chromosome 3 open reading frame 52
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Extracellular Exosome	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Carboxypeptidase Activity Metallocarboxypeptidase Activity Peptidase Activity Dipeptidase Activity Metal Ion Binding Ac-Asp-Glu Binding Tetrahydrofolyl-poly(glutamate) Polymer Binding	Protein Binding
	Biological Process	Proteolysis C-terminal Protein Deglutamylation
Pathways		Aspartate and asparagine metabolism
Drugs		Capromab pendetide Glutamic acid (2S)-2-{[HYDROXY(4-IODOBENZYL)PHOSPHORYL]METHYL}PENTANEDIOIC ACID DCFBC Spaglumic Acid
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 30072576) Body size at age 10 ( 32376654) Fasting glucose ( 34059833) Feeling fed-up ( 29500382) HDL cholesterol ( 19060911) HDL cholesterol levels ( 32203549) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Height ( 20881960) Intraocular pressure ( 29617998) Serum metabolite concentrations in chronic kidney disease ( 33838163) Serum metabolite levels ( 33031748) Systolic blood pressure ( 30578418) Systolic blood pressure x dichotomous lifestyle risk score interaction (2df test) ( 32227373) Urinary metabolite levels in chronic kidney disease ( 31959995)	Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494)
Interacting Genes		3 interacting genes: C3orf52 MTAP RPS3	72 interacting genes: ADGRG3 AGER AHNAK2 AMIGO1 AQP6 ATP1B4 BIK CCL21 CCL26 CD33 CHST13 CLDN7 CLEC10A CNMD CPLX4 CREB3 DEXI ERGIC3 ERP29 ESAM FAM209A FFAR2 FNDC9 FOLH1 FUT3 GJA8 GJB1 GOLM2 GORAB HHLA2 HSD17B13 KEL KIR2DL3 KLRC1 LEUTX LHFPL5 LMNA LRRC25 MFF MGST2 MGST3 MRGPRX3 MUC1 NCR3LG1 NEMP1 NPDC1 NSG2 PVR QPCTL REEP3 RNF150 SAR1A SGTA SIGLECL1 SLC10A2 SLC16A2 SLC23A2 SLC39A2 SPRING1 ST6GALNAC3 STOM SYNE4 TIMMDC1 TMEM179B TMEM237 TMEM45B TMEM52B TMEM80 TMPRSS2 TMX2 UPK2 ZNRF3
Entrez ID		2346	79669
HPRD ID		02961	08018
Ensembl ID		ENSG00000086205	ENSG00000114529
Uniprot IDs		Q04609	Q5BVD1
PDB IDs		1Z8L 2C6C 2C6G 2C6P 2CIJ 2JBJ 2JBK 2OOT 2OR4 2PVV 2PVW 2XEF 2XEG 2XEI 2XEJ 3BHX 3BI0 3BI1 3BXM 3D7D 3D7F 3D7G 3D7H 3IWW 3RBU 3SJE 3SJF 3SJG 3SJX 4JYW 4JZ0 4LQG 4MCP 4MCQ 4MCR 4MCS 4NGM 4NGN 4NGP 4NGQ 4NGR 4NGS 4NGT 4OC0 4OC1 4OC2 4OC3 4OC4 4OC5 4OME 4P44 4P45 4P4B 4P4D 4P4E 4P4F 4P4I 4P4J 4W9Y 4X3R 5D29 5ELY 5F09 5O5R 5O5T 5O5U 5OF0 6ETY 6EZ9 6F5L 6FE5 6H7Y 6H7Z 6HKJ 6HKZ 6RBC 6RTI 6S1X 6SGP 6SKH
Enriched GO Terms of Interacting Partners?
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