C3orf52 and ST6GALNAC3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		C3orf52	ST6GALNAC3
Description		chromosome 3 open reading frame 52	ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Golgi Membrane Nucleoplasm Integral Component Of Membrane
	Molecular Function	Protein Binding	Alpha-N-acetylgalactosaminide Alpha-2,6-sialyltransferase Activity Protein Binding Sialyltransferase Activity (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase Activity
	Biological Process		Ganglioside Biosynthetic Process Protein Glycosylation Glycosylceramide Metabolic Process Glycosphingolipid Metabolic Process Glycoprotein Metabolic Process Oligosaccharide Metabolic Process Viral Protein Processing Sialylation
Pathways			Sialic acid metabolism Maturation of protein 3a Maturation of spike protein Maturation of protein 3a Termination of O-glycan biosynthesis
Drugs
Diseases
GWAS		Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494)	Bipolar disorder ( 25827505) Liver enzyme levels (alanine transaminase) ( 24124411) Liver enzyme levels (aspartate transaminase) ( 24124411) Liver fibrogenesis (alpha smooth muscle actin levels) ( 32953199) Middle temporal gyrus volume ( 31530798) Mitochondrial DNA levels ( 25240745) Mosquito bite size ( 28199695) Parkinson's disease motor subtype (tremor dominant vs postural instability/gait difficulty) ( 33987465) Serum vitamin D-binding protein levels ( 24740207) Tau burden ( 33426524) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		72 interacting genes: ADGRG3 AGER AHNAK2 AMIGO1 AQP6 ATP1B4 BIK CCL21 CCL26 CD33 CHST13 CLDN7 CLEC10A CNMD CPLX4 CREB3 DEXI ERGIC3 ERP29 ESAM FAM209A FFAR2 FNDC9 FOLH1 FUT3 GJA8 GJB1 GOLM2 GORAB HHLA2 HSD17B13 KEL KIR2DL3 KLRC1 LEUTX LHFPL5 LMNA LRRC25 MFF MGST2 MGST3 MRGPRX3 MUC1 NCR3LG1 NEMP1 NPDC1 NSG2 PVR QPCTL REEP3 RNF150 SAR1A SGTA SIGLECL1 SLC10A2 SLC16A2 SLC23A2 SLC39A2 SPRING1 ST6GALNAC3 STOM SYNE4 TIMMDC1 TMEM179B TMEM237 TMEM45B TMEM52B TMEM80 TMPRSS2 TMX2 UPK2 ZNRF3	1 interacting genes: C3orf52
Entrez ID		79669	256435
HPRD ID		08018	15341
Ensembl ID		ENSG00000114529	ENSG00000184005
Uniprot IDs		Q5BVD1	Q8NDV1
PDB IDs
Enriched GO Terms of Interacting Partners?
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