PPP1R13B and MIPOL1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		PPP1R13B	MIPOL1
Description		protein phosphatase 1 regulatory subunit 13B	mirror-image polydactyly 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Perinuclear Region Of Cytoplasm	Nucleus
	Molecular Function	P53 Binding Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Cell Cycle Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Neuron Death
Pathways		Activation of PUMA and translocation to mitochondria TP53 Regulates Transcription of Genes Involved in Cytochrome C Release TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain TP53 Regulates Transcription of Death Receptors and Ligands Regulation of TP53 Activity through Association with Co-factors
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bitter alcoholic beverage consumption ( 31046077) Body mass index ( 26426971) General risk tolerance (MTAG) ( 30643258) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Triglycerides ( 30275531)	Eosinophil percentage of white cells ( 32888494) Estimated glomerular filtration rate ( 31152163) Intraocular pressure ( 29617998) Longitudinal alcohol consumption ( 26081443) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Mean reticulocyte volume ( 32888494) Metabolite levels ( 23823483) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Red blood cell count ( 32888494) Tonsillectomy ( 27182965 28928442)
Interacting Genes		72 interacting genes: ACSF3 APC ARHGAP45 BFSP2 BRCA1 C2orf42 CAPN7 CBY2 CCDC102B CCDC184 CCHCR1 CDC5L CEP57 CEP63 CGN CKS1B DEUP1 DGCR6L DIRAS1 DTNB FAM184A FAM90A1 GAS2L2 GINS4 GOLGA1 HMG20B HNRNPUL1 KHDRBS1 KHDRBS3 KIF9 KIFC3 KRT20 KRT4 LMNB1 LMNB2 LMO1 LMO3 LNX1 MATN4 MCRS1 MIPOL1 MIS18A MLH1 NAP1L2 NDC80 NEK7 NHSL2 PLEKHA5 PPFIA3 PPP1CA PPP1R18 PRKAB2 PRPH PRR35 RALBP1 RASAL3 RASSF8 SALL1 SOGA1 TCL1A TEKT4 TEX12 TEX9 TNIK TP63 TP73 TRAF1 TSG101 TSGA10 TXLNA ZGPAT ZZZ3	75 interacting genes: ANKRD23 ARNT2 ATP5PO BEX2 BYSL C1orf109 C1orf35 C2CD6 CCDC120 CCDC146 CCDC33 CCT3 CDC37 CDK18 CKS1B DAXX DGCR6 EAF1 EIF4E2 ENKD1 EXOC8 FAM124B FAM161A FAM161B FAM90A1 FBF1 FMNL2 GADD45GIP1 GEM HAUS1 KDF1 KIF9 LAGE3 LENG1 MAGEA6 MBD3 MCM7 MFAP1 MOS MYLIP NEBL NTAQ1 PAX6 PBX4 PKN1 PPP1R13B PRDM16 PRPF31 RBM41 RCOR3 REL RIIAD1 RNF6 RPL10L RTP5 SCNM1 SHANK3 SMARCE1 SNAP91 SNTG2 SRPK2 SSX3 STMN3 TBC1D7 TCHP TSEN15 TSGA10IP TTC12 TXN2 UBE2I UBE2K USH1C UTP25 ZGPAT ZNF688
Entrez ID		23368	145282
HPRD ID		07345	06029
Ensembl ID		ENSG00000088808	ENSG00000151338
Uniprot IDs		Q96KQ4	A8K735 G5EA54 Q4G0U7 Q8TD10
PDB IDs		6HL5
Enriched GO Terms of Interacting Partners?
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