WWC1 and DDN

Number of citations of the paper that reports this interaction (PubMedID 12559952)
63

Data Source:
HPRD (two hybrid)

		WWC1	DDN
Description		WW and C2 domain containing 1	dendrin
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Ruffle Membrane Protein-containing Complex Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Dendritic Spine Membrane Cell Projection Perikaryon Postsynaptic Membrane
	Molecular Function	Transcription Coactivator Activity Protein Binding Kinase Binding Molecular Adaptor Activity	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Cell Migration Establishment Of Cell Polarity Regulation Of Intracellular Transport Regulation Of Hippo Signaling Negative Regulation Of Hippo Signaling Positive Regulation Of MAPK Cascade Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Organ Growth
Pathways		Signaling by Hippo NOTCH3 Intracellular Domain Regulates Transcription
Drugs
Diseases
GWAS		Adult body size ( 32376654) Cerebellum cortex volume ( 31530798) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Epithelial ovarian cancer ( 31469419) Mental health study participation (provided email address) ( 31263887) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Number of sexual partners ( 30643258) Periodontal microbiota ( 22699663) Regular attendance at a religious group ( 29970889) Type 2 diabetes nephropathy including microalbuminuria ( 30566433)	Bipolar disorder ( 28115744 31043756 27329760) Heel bone mineral density ( 30598549 28869591)
Interacting Genes		15 interacting genes: AIFM1 CDC5L CDC73 DDN FAM219A FEZ1 FEZ2 H3C1 KIAA0513 LRIF1 MAPK6 PRKCZ TNIK WWC2 WWC3	6 interacting genes: DIP2B DNAJC22 FKBP11 MCRS1 TROAP WWC1
Entrez ID		23286	23109
HPRD ID		10033	10294
Ensembl ID		ENSG00000113645	ENSG00000181418
Uniprot IDs		Q8IX03	O94850
PDB IDs		2Z0U 6FB4 6FD0 6FJC 6FJD
Enriched GO Terms of Interacting Partners?
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