WWC1 and TNIK

  • Number of citations of the paper that reports this interaction (PubMedID 17043677)
  • 193
  • Data Source:
  • BioGRID (two hybrid)

WWC1

TNIK

Description WW and C2 domain containing 1 TRAF2 and NCK interacting kinase
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Cerebellum cortex volume ( 31530798)
  • Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189)
  • Epithelial ovarian cancer ( 31469419)
  • Mental health study participation (provided email address) ( 31263887)
  • Metabolite levels ( 23823483)
  • Night sleep phenotypes ( 27126917)
  • Number of sexual partners ( 30643258)
  • Periodontal microbiota ( 22699663)
  • Regular attendance at a religious group ( 29970889)
  • Type 2 diabetes nephropathy including microalbuminuria ( 30566433)
  • Adolescent idiopathic scoliosis ( 28334814)
  • Brain imaging in schizophrenia (dorsolateral prefrontal cortex interaction) ( 19023125)
  • Brain morphology (min-P) ( 32665545)
  • Brain morphology (MOSTest) ( 32665545)
  • Cerebrospinal fluid AB1-42 levels ( 29274321)
  • Change in serum metabolite levels ( 31636271)
  • Change in serum metabolite levels (CMS) ( 31636271)
  • Cortical surface area (MOSTest) ( 32665545)
  • Estimated glomerular filtration rate after 1 year in renal transplantation (recipient effect) ( 30920136)
  • Frontotemporal dementia (age at onset) ( 29724592)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • Hip circumference adjusted for BMI ( 28552196)
  • LDL cholesterol ( 21347282)
  • Lymphocyte counts ( 32888494 27863252)
  • Lymphocyte percentage of white cells ( 32888494)
  • Night sleep phenotypes ( 27126917)
  • Response to antipsychotic treatment in schizophrenia ( 29503163)
  • Subcortical volume (MOSTest) ( 32665545)
  • Triglyceride levels ( 32154731)
  • Type 2 diabetes ( 30054458)
Interacting Genes 15 interacting genes: AIFM1 CDC5L CDC73 DDN FAM219A FEZ1 FEZ2 H3C1 KIAA0513 LRIF1 MAPK6 PRKCZ TNIK WWC2 WWC3 37 interacting genes: ACTG1 AGTPBP1 AKAP9 ANK2 CLU CNKSR2 DPYSL2 DPYSL3 DST DYNC1H1 GOLGA4 GSE1 GSN HARS1 MACF1 NCK1 NCOR2 NEDD4 NEFM PAFAH1B1 PDE4DIP PPM1E PPP1R13B RAP2A SMARCE1 SMURF1 SNX6 SOS1 SPTBN1 SRGAP3 SYNE1 TIAM2 TNKS TRAF2 TRIM2 TUBB2A WWC1
Entrez ID 23286 23043
HPRD ID 10033 18206
Ensembl ID ENSG00000113645 ENSG00000154310
Uniprot IDs Q8IX03 Q9UKE5
PDB IDs 2Z0U 6FB4 6FD0 6FJC 6FJD 2X7F 5AX9 5CWZ 5D7A 6RA5 6RA7
Enriched GO Terms of Interacting Partners?
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