WWC1 and FAM219A

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		WWC1	FAM219A
Description		WW and C2 domain containing 1	family with sequence similarity 219 member A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Ruffle Membrane Protein-containing Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Transcription Coactivator Activity Protein Binding Kinase Binding Molecular Adaptor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Cell Migration Establishment Of Cell Polarity Regulation Of Intracellular Transport Regulation Of Hippo Signaling Negative Regulation Of Hippo Signaling Positive Regulation Of MAPK Cascade Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Organ Growth
Pathways		Signaling by Hippo NOTCH3 Intracellular Domain Regulates Transcription
Drugs
Diseases
GWAS		Adult body size ( 32376654) Cerebellum cortex volume ( 31530798) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Epithelial ovarian cancer ( 31469419) Mental health study participation (provided email address) ( 31263887) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Number of sexual partners ( 30643258) Periodontal microbiota ( 22699663) Regular attendance at a religious group ( 29970889) Type 2 diabetes nephropathy including microalbuminuria ( 30566433)
Interacting Genes		15 interacting genes: AIFM1 CDC5L CDC73 DDN FAM219A FEZ1 FEZ2 H3C1 KIAA0513 LRIF1 MAPK6 PRKCZ TNIK WWC2 WWC3	8 interacting genes: CSNK1G1 LIMS3 LIMS4 NIPSNAP3A PDE6D POLA2 SPRY2 WWC1
Entrez ID		23286	203259
HPRD ID		10033	12950
Ensembl ID		ENSG00000113645	ENSG00000164970
Uniprot IDs		Q8IX03	Q8IW50
PDB IDs		2Z0U 6FB4 6FD0 6FJC 6FJD
Enriched GO Terms of Interacting Partners?
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