MTUS2 and WAC

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		MTUS2	WAC
Description		microtubule associated scaffold protein 2	WW domain containing adaptor with coiled-coil
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Centrosome Cytoplasmic Microtubule	Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	Protein Binding Microtubule Binding Protein Homodimerization Activity	RNA Polymerase II Complex Binding Chromatin Binding Protein Binding
	Biological Process		Cellular Response To DNA Damage Stimulus Histone Monoubiquitination Regulation Of Autophagy Positive Regulation Of Macroautophagy Mitotic G1 DNA Damage Checkpoint Signaling Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Transcription, DNA-templated Histone H2B Conserved C-terminal Lysine Ubiquitination Positive Regulation Of TORC1 Signaling
Pathways			E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		HDL cholesterol levels in HIV infection ( 33109212) Hypertrophic cardiomyopathy (sarcomere positive) ( 33495597) Insomnia (caffeine-induced) ( 22754043) Obesity-related traits ( 23251661) Triptolide cytotoxicity ( 26121980)	Diastolic blood pressure ( 30224653) Intraocular pressure ( 29617998) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Multiple myeloma ( 27363682)
Interacting Genes		327 interacting genes: - ABHD15 ACSM1 AEN AFF4 AKT1 ANKRD11 ANKS1A AQP1 ARL4A ARNT2 AXIN1 BANF2 BARD1 BCL6 BEX2 BMP7 BYSL C19orf44 C1orf109 C1orf216 C1orf35 C21orf58 C2CD6 C8orf34 CACNB3 CATIP CATSPER1 CBX8 CCAR1 CCDC116 CCDC120 CCDC146 CCDC17 CCDC185 CCDC187 CCDC198 CCDC6 CCDC60 CCHCR1 CDC20B CDC5L CDC7 CDC73 CDK18 CDK5R1 CDKL3 CDKN1A CDKN1B CEP57L1 CEP95 CERK CHIC2 CNNM3 COG2 CREB5 CRY2 CSF1 CTSZ CWF19L2 CXCL11 CXCL16 CYSLTR2 DCDC2B DCTN4 DCX DDX6 DHRS1 DLGAP4 DLGAP5 DMRT3 DOCK2 DTNB EHHADH EIF3D ENKD1 ENPP7 EXOC8 FAM107A FAM110A FAM124B FAM13C FAM161A FAM161B FAM71E2 FAM74A4 FAM90A1 FASTKD5 FBXL18 FBXO34 FBXW5 FCHSD2 FHL3 FLYWCH1 FNDC11 FXR1 GADD45GIP1 GAL3ST2 GAS2L2 GEM GGN GNL3L GOLGA2P11 GPKOW GRAP2 GSTP1 GTF2I GTPBP10 HAPLN2 HAUS1 HBZ HCK HDAC4 HOXB5 HOXB9 HSF2 ICAM4 IL16 INO80B IQCE ITGB4 ITGB5 ITSN1 JMY JOSD1 JRK KANK2 KAT5 KIF1A KIFC3 KRT6A KRT75 KRT76 LENG1 LIMS2 LINC00636 LMO2 LMO3 LMO4 LNX1 LRR1 LYSMD1 MAGEA8 MARK4 MBD3 METTL17 MFAP1 MOS MRPL11 MTMR6 MYO15B MYOM1 MYPOP NDEL1 NDOR1 NEFL NELFE NHSL2 NTAQ1 NUBPL NUDT10 NXF1 ODAD3 ODF1 PCDHB14 PDE4DIP PDZD4 PIBF1 PIN1 PKN1 PKN3 PKP2 PLEKHN1 PLK4 PLSCR4 POLDIP2 POLDIP3 PPHLN1 PPP1R18 PRKAA1 PRKAA2 PRPF18 PRPF31 PRR35 PSMA1 PSMB1 PTCD1 PTK7 PTPMT1 RAB3IL1 RALY RANBP3L RAP1B RASAL3 RASD1 RBM41 RCOR3 RGS2 RHPN1 RIBC2 RNF6 ROBO3 RPA1 RPL9 RPS19BP1 RTP5 SAMD4A SCEL SCNM1 SDCBP SELENOM SETD5 SH2D4A SH3RF2 SHFL SLC22A5 SLC23A1 SLC25A42 SLC25A48 SLC25A6 SLIRP SMARCD1 SMARCE1 SMG9 SNAI1 SNHG11 SNRPA SNRPB2 SNW1 SPATA8 SPATC1L SPG21 SPG7 STK16 SYT6 TACO1 TAF13 TBC1D22B TCEA2 TCEANC TCHP TEAD4 TEPSIN THAP7 TLE5 TNIP3 TNNI1 TP53RK TRIM29 TRIM42 TSGA10IP TSHZ3 TTC23 TTLL10 TULP2 TXN2 UBTFL1 USP2 USP22 UTP14C VASN WAC ZBTB16 ZBTB38 ZBTB47 ZC2HC1C ZFC3H1 ZFHX3 ZFP1 ZFP2 ZFP64 ZFYVE21 ZMAT2 ZMYND10 ZNF124 ZNF136 ZNF17 ZNF20 ZNF224 ZNF23 ZNF230 ZNF232 ZNF239 ZNF250 ZNF266 ZNF3 ZNF329 ZNF337 ZNF35 ZNF408 ZNF410 ZNF414 ZNF415 ZNF417 ZNF426 ZNF438 ZNF439 ZNF440 ZNF48 ZNF490 ZNF497 ZNF512B ZNF557 ZNF564 ZNF572 ZNF580 ZNF581 ZNF587 ZNF599 ZNF607 ZNF613 ZNF624 ZNF648 ZNF655 ZNF669 ZNF670 ZNF696 ZNF76 ZNF764 ZNF774 ZNF775 ZNF785 ZNF792 ZNF837 ZNF844 ZSCAN12 ZSCAN26	25 interacting genes: AKAP9 APP CCDC6 CDC37 CRKL DYDC1 HMG20B KLC3 KRT15 LNX1 MOBP MTUS2 NDE1 NFE2L2 POLR2A SYTL5 TFIP11 TNS2 TRAF1 TRAF3IP1 TRAF3IP3 UBQLN4 VCP VCPIP1 ZDHHC17
Entrez ID		23281	51322
HPRD ID		11108	18291
Ensembl ID		ENSG00000132938	ENSG00000095787
Uniprot IDs		Q5JR59	Q9BTA9
PDB IDs
Enriched GO Terms of Interacting Partners?
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