SHANK2 and DNAJC19

		SHANK2	DNAJC19
Description		SH3 and multiple ankyrin repeat domains 2	DnaJ heat shock protein family (Hsp40) member C19
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Cellular_component Cytosol Neurofilament Plasma Membrane Postsynaptic Density Apical Plasma Membrane Growth Cone Brush Border Membrane Neuron Projection Neuronal Cell Body Dendritic Spine Postsynaptic Membrane Ciliary Membrane	PAM Complex, Tim23 Associated Import Motor Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane Protein-containing Complex Inner Mitochondrial Membrane Protein Complex Matrix Side Of Mitochondrial Inner Membrane
	Molecular Function	Protein Binding SH3 Domain Binding Synaptic Receptor Adaptor Activity Ionotropic Glutamate Receptor Binding	ATPase Activator Activity Protein Binding
	Biological Process	Synapse Assembly Learning Positive Regulation Of Cell Population Proliferation Adult Behavior Social Behavior Negative Regulation Of Hippo Signaling Long-term Synaptic Potentiation Long-term Synaptic Depression Vocalization Behavior	Protein Folding Protein Targeting To Mitochondrion Visual Perception Protein Import Into Mitochondrial Matrix Genitalia Development Regulation Of Catalytic Activity Regulation Of Cardiolipin Metabolic Process
Pathways		Neurexins and neuroligins Neurexins and neuroligins	Mitochondrial protein import
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hip circumference ( 28552196) Hodgkin's lymphoma ( 34216518) Kawasaki disease ( 33692975) Late-onset Alzheimer's disease ( 27770636) Obesity-related traits ( 23251661) Response to fenofibrate (adiponectin levels) ( 23149075) Urate levels in obese individuals ( 25811787)	Schizophrenia ( 28991256 25056061 29483656 30285260)
Interacting Genes		33 interacting genes: ACE2 ADGRB2 ADGRL1 ADGRL2 ANO1 ARHGAP12 ARHGEF7 BAIAP2 BANF1 CLCF1 CTTN DLG4 DLGAP1 DLGAP2 DLGAP3 DLGAP4 DNAJC19 DNM1 DNM2 GMNN HOMER1 MCF2 ORC2 PEX3 PPFIA1 PPP3CA PRSS1 RAB6A RHOT1 RIPOR3 SHARPIN SLC9A3 SSTR2	9 interacting genes: APP CETN3 CLIC1 F11 HSPA9 LRRFIP2 MCPH1 PHTF1 SHANK2
Entrez ID		22941	131118
HPRD ID		04479	12349
Ensembl ID		ENSG00000162105	ENSG00000205981
Uniprot IDs		A0A590UJ45 A6NHU9 C0SPH0 Q9UPX8	A0A0S2Z5X1 Q96DA6
PDB IDs
Enriched GO Terms of Interacting Partners?
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