CEP164 and ATRIP

Number of citations of the paper that reports this interaction (PubMedID 18283122)
37

Data Source:
BioGRID (affinity chromatography technology, pull down)

		CEP164	ATRIP
Description		centrosomal protein 164	ATR interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleoplasm Centrosome Centriole Cytosol Ciliary Transition Fiber	Nucleoplasm
	Molecular Function	Protein Binding	Protein Binding K63-linked Polyubiquitin Modification-dependent Protein Binding
	Biological Process	DNA Repair Cell Cycle Cell Division Cilium Assembly	DNA Damage Checkpoint Signaling DNA Repair
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	Activation of ATR in response to replication stress HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Fanconi Anemia Pathway Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Diastolic blood pressure ( 30578418) Diffusing capacity of carbon monoxide ( 30694715) Hematocrit ( 32888494) Hemoglobin levels ( 32327693) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Metabolite levels ( 23823483) Pulse pressure ( 28135244 27841878 30578418)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		6 interacting genes: ATP5MG ATR ATRIP CLP1 MAPK14 UBC	22 interacting genes: BRCA1 C1orf94 CCDC28B CDC23 CDC6 CDK16 CEP164 CINP FAAP100 FAM156A LNX1 METTL21A MID2 MOS MX2 POLR1C PRKDC RPA3 SCG2 SPRY2 TASOR2 ZBTB14
Entrez ID		22897	84126
HPRD ID		10854
Ensembl ID		ENSG00000110274	ENSG00000164053
Uniprot IDs		Q9UPV0	A0A024R2U4 A0A024R307 Q8WXE1
PDB IDs			4IGK 4NB3 5YZ0
Enriched GO Terms of Interacting Partners?
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