RHOBTB3 and EFHC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RHOBTB3	EFHC2
Description		Rho related BTB domain containing 3	EF-hand domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Cell Cortex Cytoplasmic Vesicle Trans-Golgi Network Membrane Cell Projection Extracellular Exosome	Microtubule Axoneme Ciliary Basal Body Mitotic Spindle
	Molecular Function	GTPase Activity Protein Binding ATP Binding GTP Binding ATP Hydrolysis Activity Protein Kinase Binding Small GTPase Binding	Calcium Ion Binding Protein Binding Alpha-tubulin Binding
	Biological Process	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Male Gonad Development Cell Migration Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Retrograde Transport, Endosome To Golgi	Mitotic Cytokinesis Mitotic Spindle Organization Regulation Of Neuron Projection Development Cilium-dependent Cell Motility Cellular Response To Leukemia Inhibitory Factor
Pathways		Retrograde transport at the Trans-Golgi-Network RHOBTB3 ATPase cycle
Drugs
Diseases
GWAS			Body mass index and diastolic blood pressure (bivariate analysis) ( 33539483) Glaucoma (primary open-angle) ( 33627673) Mean arterial pressure ( 29403010)
Interacting Genes		17 interacting genes: BHLHE40 CCNE1 CUL3 EFHC2 HGS IHO1 L3MBTL3 PLAGL2 RAB9A RBPMS RBX1 RHOBTB2 TBX15 UBXN11 USP54 VHL ZRANB1	100 interacting genes: - AASDHPPT ARHGEF5 ARMC7 CABP2 CACNB4 CARD9 CCDC102B CCDC120 CCDC13 CCDC57 CCHCR1 CCNG2 CDKN2A CLIC3 COPE CPNE2 CPNE7 CYFIP1 DCLK1 DDX6 DGCR6 DRC7 EDC3 EFHC1 EGLN3 EMD ENKD1 ESRRG EXOC8 EXOSC5 FAM107A FAM124B FAM214B FAM221B FBXL19 GEM GLYCTK GOLGA1 GPKOW GRB2 GYS1 HDAC4 HGS HNRNPLL INPP5J JAKMIP2 KANK2 KCTD7 KIF9 L3MBTL2 LMNB2 LMO2 LNX1 LONRF1 MAGOHB MAPK9 MID2 MISP MYLIP MYO5B NCDN NCK2 NDOR1 NEK6 NFKBID NME7 NR3C1 PBLD PHF1 PIBF1 PICK1 PLOD3 POLR1C PRPF18 PTK6 QARS1 RAD51D RCOR3 RECK RHOBTB3 RUNX1T1 SNRNP25 SOGA1 SPATA18 SPG21 STK16 TBC1D1 TBC1D22B TEKT4 TRIM42 TRIM50 TSSK3 TUBGCP4 TXK U2AF1 USP2 ZBTB16 ZFHX3 ZZZ3
Entrez ID		22836	80258
HPRD ID		09557	06540
Ensembl ID		ENSG00000164292	ENSG00000183690
Uniprot IDs		O94955	Q5JST6
PDB IDs			2Z13 2Z14
Enriched GO Terms of Interacting Partners?
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