FDFT1 and SLC10A1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FDFT1	SLC10A1
Description		farnesyl-diphosphate farnesyltransferase 1	solute carrier family 10 member 1
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane
	Molecular Function	Farnesyl-diphosphate Farnesyltransferase Activity Protein Binding Metal Ion Binding Squalene Synthase Activity	Virus Receptor Activity Protein Binding Bile Acid:sodium Symporter Activity
	Biological Process	Steroid Biosynthetic Process Cholesterol Biosynthetic Process Farnesyl Diphosphate Metabolic Process	Sodium Ion Transport Regulation Of Gene Expression Bile Acid And Bile Salt Transport Response To Nutrient Levels Bile Acid Signaling Pathway Response To Ethanol Viral Entry Into Host Cell Transmembrane Transport Cellular Response To Xenobiotic Stimulus Regulation Of Bile Acid Secretion Response To 17alpha-ethynylestradiol
Pathways		Cholesterol biosynthesis PPARA activates gene expression Activation of gene expression by SREBF (SREBP)	Recycling of bile acids and salts
Drugs		TAK-475
Diseases
GWAS		Blood protein levels ( 28240269) Body shape index ( 34021172) Brain morphology (MOSTest) ( 32665545) C-reactive protein levels ( 30388399) Ejection fraction in Tripanosoma cruzi seropositivity ( 24324551) Fish- and plant-related diet ( 32066663) General factor of neuroticism ( 30867560) Heschl's gyrus morphology ( 25130324) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Non-alcoholic fatty liver disease histology (lobular) ( 20708005) Non-alcoholic fatty liver disease histology (other) ( 20708005) Platelet count ( 32888494) Polycystic ovary syndrome ( 26284813) Processed meat consumption ( 32066663) Refractive error ( 32231278) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Daytime sleep phenotypes ( 27126917) Metabolite levels ( 23823483) Triglyceride levels ( 30108155)
Interacting Genes		26 interacting genes: ANXA5 AQP6 ARL13B ARL6IP1 CD74 CD79A CLN5 CREB3 ELOVL4 ELP4 FAM209A GJA8 GPR152 ITGB5 JAGN1 LMNA NCAPH2 PANX1 RFLNA RUVBL2 SHPRH SLC10A1 SLC35C2 TLCD4 TMEM43 TMX2	91 interacting genes: ABHD16A ACSL5 AGPAT3 ARL6IP6 ASGR1 ATP6V0B BMP10 C2 C8A CFHR5 CLDN19 CMTM3 COX20 CXCL9 CYB5R3 DERL1 DGAT2L6 FA2H FAM241B FAXDC2 FCER1G FDFT1 FXYD3 FXYD6 FXYD6-FXYD2 GAST GDE1 GIMAP5 GOSR2 GPR151 GPR152 IFITM2 IFITM3 IFTAP LRP10 LSS MAL MALL MFSD6 MS4A1 MYADML2 NEU1 NINJ2 ORMDL1 ORMDL2 ORMDL3 OTOP3 PEDS1-UBE2V1 PEX16 PKMYT1 RUSF1 SACM1L SCAMP4 SELENOK SFT2D1 SFT2D2 SFXN1 SLC12A7 SLC16A13 SLC25A46 SLC29A2 SLC35E4 SLC38A1 SLC38A7 SLC41A1 SLC66A2 SLC7A3 SMPD2 STX7 TAP1 TFRC TMBIM1 TMEM119 TMEM120B TMEM121 TMEM147 TMEM222 TMEM234 TMEM239 TMEM242 TMEM60 TMUB2 TOMM6 TRARG1 TSPO2 TVP23B UNC50 VAMP3 YIF1A YIPF4 YIPF6
Entrez ID		2222	6554
HPRD ID		01694	01672
Ensembl ID		ENSG00000079459	ENSG00000100652
Uniprot IDs		A0A1W2PQ47 B4DND3 B4DWP0 B7Z9R8 P37268 Q6IAX1	B2RA41 Q14973
PDB IDs		1EZF 3ASX 3LEE 3Q2Z 3Q30 3V66 3VJ8 3VJ9 3VJA 3VJB 3VJC 3WC9 3WCD 3WCF 3WCH 3WCI 3WCJ 3WCL 3WCM 3WEF 3WEG 3WEH 3WEI 3WEJ 3WEK 3WSA 6PYJ 6PYV 6PYW 6PZ5
Enriched GO Terms of Interacting Partners?
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