CCDC125 and ZNF343

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CCDC125	ZNF343
Description		coiled-coil domain containing 125	zinc finger protein 343
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus
	Molecular Function	Molecular_function Protein Binding Identical Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Rho Protein Signal Transduction Activation Of GTPase Activity Negative Regulation Of Cell Motility	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Lymphocyte percentage of white cells ( 32888494) Monocyte percentage of white cells ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494 27863252) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252)	Conotruncal heart defects (maternal effects) ( 28468790) Glomerular filtration rate in chronic kidney disease ( 26420894)
Interacting Genes		64 interacting genes: BMP7 C1orf109 C21orf58 C22orf15 C4orf45 CCNG1 CDC23 CDK18 CEP95 EIF3D FAM107A FAM161A FAM161B FAM214B FAM47B FLYWCH1 GAS8 GEM HAPLN2 HDAC4 KAT5 KIF9 KRTAP13-2 LCE2C MYH1 NEBL NSD1 NSMF OTOS PKP2 PRPF3 PTPA RAB2A RIPOR3 SFN SNW1 STX11 TCHP TEAD4 TRIM14 TSGA10IP UACA YWHAE YWHAH YWHAQ YWHAZ ZFP1 ZFYVE26 ZNF165 ZNF230 ZNF250 ZNF32 ZNF337 ZNF343 ZNF417 ZNF436 ZNF552 ZNF557 ZNF564 ZNF587 ZNF764 ZNF792 ZNF837 ZNF883	24 interacting genes: ACTN3 APP BFSP2 CCDC125 FAM90A1 FASTKD5 JRK KLC4 NEK6 NME7 NUDT22 NXF1 PAX9 RAD51D RUNX1T1 SDCBP STK16 TEPSIN TRIM41 UBQLN1 USP20 ZNF319 ZNF648 ZNF835
Entrez ID		202243	79175
HPRD ID		13774	18327
Ensembl ID		ENSG00000183323	ENSG00000088876
Uniprot IDs		B4DSR1 Q2HJ12 Q86Z20	A0A087WZQ2 Q6P1L6
PDB IDs
Enriched GO Terms of Interacting Partners?
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