CCDC125 and ZFYVE26

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CCDC125	ZFYVE26
Description		coiled-coil domain containing 125	zinc finger FYVE-type containing 26
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Lysosomal Membrane Centrosome Midbody
	Molecular Function	Molecular_function Protein Binding Identical Protein Binding	Protein Binding Phosphatidylinositol-3-phosphate Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Rho Protein Signal Transduction Activation Of GTPase Activity Negative Regulation Of Cell Motility	Mitotic Cytokinesis Double-strand Break Repair Via Homologous Recombination Regulation Of Cytokinesis
Pathways
Drugs
Diseases
GWAS		Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Lymphocyte percentage of white cells ( 32888494) Monocyte percentage of white cells ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494 27863252) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Asthma ( 31959851) Asthma (childhood onset) ( 31036433)
Interacting Genes		64 interacting genes: BMP7 C1orf109 C21orf58 C22orf15 C4orf45 CCNG1 CDC23 CDK18 CEP95 EIF3D FAM107A FAM161A FAM161B FAM214B FAM47B FLYWCH1 GAS8 GEM HAPLN2 HDAC4 KAT5 KIF9 KRTAP13-2 LCE2C MYH1 NEBL NSD1 NSMF OTOS PKP2 PRPF3 PTPA RAB2A RIPOR3 SFN SNW1 STX11 TCHP TEAD4 TRIM14 TSGA10IP UACA YWHAE YWHAH YWHAQ YWHAZ ZFP1 ZFYVE26 ZNF165 ZNF230 ZNF250 ZNF32 ZNF337 ZNF343 ZNF417 ZNF436 ZNF552 ZNF557 ZNF564 ZNF587 ZNF764 ZNF792 ZNF837 ZNF883	35 interacting genes: ALAS1 ASB15 CBY2 CCDC125 CCDC136 CEP44 GOLGA2 GPRASP2 HMBOX1 HNRNPC HOOK2 KRT15 KRT27 KRT34 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 MAGED1 MDFI PLEKHF2 PNMA1 PNMA5 PPP1R16A PRDM6 SPAG5 SSX2IP TADA2A TCEANC TDO2 TFIP11 TRAF1 TTC23 USHBP1 USP20
Entrez ID		202243	23503
HPRD ID		13774	15734
Ensembl ID		ENSG00000183323	ENSG00000072121
Uniprot IDs		B4DSR1 Q2HJ12 Q86Z20	A0A7I2YQU3 Q68DK2
PDB IDs
Enriched GO Terms of Interacting Partners?
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