EMX1 and HOXA10

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		EMX1	HOXA10
Description		empty spiracles homeobox 1	homeobox A10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Chromosome Nucleolus Cytoplasm	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Histone Deacetylase Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	In Utero Embryonic Development Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Brain Development Response To Xenobiotic Stimulus Post-embryonic Development Cerebral Cortex Regionalization Cerebral Cortex Neuron Differentiation Neuron Differentiation Brain Morphogenesis Homeostasis Of Number Of Cells Radial Glial Cell Differentiation Neuroepithelial Cell Differentiation Regulation Of Oligodendrocyte Progenitor Proliferation Neuron Projection Extension	Skeletal System Development Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Spermatogenesis Single Fertilization Male Gonad Development Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Embryonic Limb Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Uterus Development
Pathways
Drugs			Calcitriol
Diseases
GWAS		Malaria ( 31844061) Schizophrenia ( 28991256 30285260)	Dental caries ( 23259602) Hypertension ( 31879980 30487518) Mean arterial pressure ( 30487518) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		8 interacting genes: ALX4 ELK1 GTF2A1L HOXA10 LINC00839 POLR2D PRDM4 TP63	16 interacting genes: CREBBP EMX1 EP300 FOXO1 GMNN GNG13 HMGB1 MAD1L1 MEIS1 NAB2 PBX1 POLR3D PTPN6 SIRT2 SNAPC1 SPI1
Entrez ID		2016	3206
HPRD ID		08963	00845
Ensembl ID		ENSG00000135638	ENSG00000253293
Uniprot IDs		Q04741	P31260
PDB IDs
Enriched GO Terms of Interacting Partners?
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