EMP1 and ATP6V0E1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		EMP1	ATP6V0E1
Description		epithelial membrane protein 1	ATPase H+ transporting V0 subunit e1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Lysosomal Membrane Endosome Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain
	Molecular Function	Protein Binding	Protein Binding Hydrolase Activity ATPase-coupled Ion Transmembrane Transporter Activity Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Cell Death Epidermis Development Bleb Assembly	Vacuolar Acidification Regulation Of Macroautophagy Transmembrane Transport Proton Transmembrane Transport
Pathways			ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS		Coronary artery calcification ( 23870195) Degraded stimulus continuous performance test score ( 31596458) Estimated glomerular filtration rate after 1 year in renal transplantation (donor effect) ( 30920136) Heel bone mineral density ( 30598549 28869591) Household income (MTAG) ( 31844048) Refractive error ( 32231278) Serum albumin level ( 29403010)	Body mass index ( 27455349) PR interval ( 32439900)
Interacting Genes		63 interacting genes: ANK1 ANKS6 APOL2 AQP6 ARL13B ARL6IP1 ASGR2 ATP6V0B ATP6V0E1 BTN2A2 C1QBP CCR5 CD37 CD3G CD40 CD53 CD79A CEP70 CLDN9 CORIN CXCR2 EBP EDA EHHADH ERGIC3 FFAR2 GIMAP5 GPR42 GPRC5D HTR2C ISLR2 JPH1 KLRC1 LAPTM4B LEPROTL1 LHFPL5 LPAR6 LRRC3B LSMEM2 MAL MALL MS4A7 OPRM1 PLEKHB2 PMP22 RABAC1 RPRM SERTM1 SMIM3 SPACA1 STOM SYNE4 TBXA2R TEX264 TLCD4 TMEM114 TMEM160 TMEM218 TMEM239 TMEM262 TMEM31 TMEM9 TSPO2	19 interacting genes: - APOD ATP6V1E1 CDIPT COL8A2 CXCL16 EMP1 GPR25 KIR2DL3 MAL2 MS4A13 MS4A4A NAT8 OPRM1 PLN SYT15 TMEM218 TMEM254 YIPF6
Entrez ID		2012	8992
HPRD ID		11892	04894
Ensembl ID		ENSG00000134531	ENSG00000113732
Uniprot IDs		A0A024RAT0 P54849	O15342
PDB IDs			6WLW 6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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