ATP6V0E1 and KIR2DL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ATP6V0E1	KIR2DL3
Description		ATPase H+ transporting V0 subunit e1	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3
Image
GO Annotations	Cellular Component	Lysosomal Membrane Endosome Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Hydrolase Activity ATPase-coupled Ion Transmembrane Transporter Activity Proton-transporting ATPase Activity, Rotational Mechanism	Antigen Binding Protein Binding Signaling Receptor Activity Identical Protein Binding
	Biological Process	Vacuolar Acidification Regulation Of Macroautophagy Transmembrane Transport Proton Transmembrane Transport	Immune Response
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs		Tiludronic acid
Diseases
GWAS		Body mass index ( 27455349) PR interval ( 32439900)
Interacting Genes		19 interacting genes: - APOD ATP6V1E1 CDIPT COL8A2 CXCL16 EMP1 GPR25 KIR2DL3 MAL2 MS4A13 MS4A4A NAT8 OPRM1 PLN SYT15 TMEM218 TMEM254 YIPF6	64 interacting genes: ADGRE2 AGTRAP AIG1 ANKRD46 APOA2 APOD APP AQP10 ASGR1 ATP6V0E1 BMP10 BRICD5 BTN2A2 C3orf52 CDIPT CISD2 CLDN19 CLN6 COQ9 CXCL16 CXCL9 CYB5B CYBC1 EMD FAM209A FAM3C FUNDC2 GAST GJA8 GPR108 GPX8 HLA-C IFITM3 INSIG2 ITGAM JAGN1 KTN1 LAT LCK LEUTX LHFPL5 NINJ2 NRM NSG1 OLFM4 PLN PLPPR2 PTPN6 RNF152 RTP2 SEC22B SLC38A7 SMIM1 SNORC THBD TMEM218 TMEM222 TMEM243 TMEM86B TMEM97 TRAF3IP3 UPK1B UPK2 VAMP5
Entrez ID		8992	3804
HPRD ID		04894	10383
Ensembl ID		ENSG00000113732	ENSG00000243772
Uniprot IDs		O15342	E3NZD8 P43628
PDB IDs		6WLW 6WM2 6WM3 6WM4	1B6U 6PAG
Enriched GO Terms of Interacting Partners?
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