EMP1 and EDA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		EMP1	EDA
Description		epithelial membrane protein 1	ectodysplasin A
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Collagen Trimer Extracellular Space Endoplasmic Reticulum Membrane Lipid Droplet Cytoskeleton Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Apical Part Of Cell
	Molecular Function	Protein Binding	Signaling Receptor Binding Death Receptor Binding Tumor Necrosis Factor Receptor Binding Protein Binding Death Receptor Agonist Activity Receptor Ligand Activity
	Biological Process	Cell Death Epidermis Development Bleb Assembly	Immune Response Cell-matrix Adhesion Signal Transduction Gene Expression Positive Regulation Of Gene Expression Cell Differentiation Odontogenesis Of Dentin-containing Tooth Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Pigmentation Animal Organ Development Positive Regulation Of NF-kappaB Transcription Factor Activity Salivary Gland Cavitation Hair Follicle Placode Formation Trachea Gland Development Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of NIK/NF-kappaB Signaling
Pathways			TNFs bind their physiological receptors
Drugs
Diseases
GWAS		Coronary artery calcification ( 23870195) Degraded stimulus continuous performance test score ( 31596458) Estimated glomerular filtration rate after 1 year in renal transplantation (donor effect) ( 30920136) Heel bone mineral density ( 30598549 28869591) Household income (MTAG) ( 31844048) Refractive error ( 32231278) Serum albumin level ( 29403010)	Male-pattern baldness ( 30573740) Metabolite levels ( 23823483) Monobrow ( 27182965) Primary tooth development (number of teeth) ( 23704328 20195514) Primary tooth development (time to first tooth eruption) ( 23704328 20195514) Tooth agenesis (maxillary lateral incisors) ( 29364747)
Interacting Genes		63 interacting genes: ANK1 ANKS6 APOL2 AQP6 ARL13B ARL6IP1 ASGR2 ATP6V0B ATP6V0E1 BTN2A2 C1QBP CCR5 CD37 CD3G CD40 CD53 CD79A CEP70 CLDN9 CORIN CXCR2 EBP EDA EHHADH ERGIC3 FFAR2 GIMAP5 GPR42 GPRC5D HTR2C ISLR2 JPH1 KLRC1 LAPTM4B LEPROTL1 LHFPL5 LPAR6 LRRC3B LSMEM2 MAL MALL MS4A7 OPRM1 PLEKHB2 PMP22 RABAC1 RPRM SERTM1 SMIM3 SPACA1 STOM SYNE4 TBXA2R TEX264 TLCD4 TMEM114 TMEM160 TMEM218 TMEM239 TMEM262 TMEM31 TMEM9 TSPO2	24 interacting genes: ATP6V0C CTXN3 CYB561 DOLK EDA2R EDAR EMP1 EMP3 FURIN GIMAP5 LEPROTL1 LPAR3 MAL MS4A13 NIPAL3 OSTC OSTCP1 PLN PMP22 SEC22A SLC38A7 TMEM42 TMEM50B TMEM60
Entrez ID		2012	1896
HPRD ID		11892	02347
Ensembl ID		ENSG00000134531	ENSG00000158813
Uniprot IDs		A0A024RAT0 P54849	A0A0U5J797 Q92838
PDB IDs			1RJ7 1RJ8
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?