SCAMP5 and SH3GL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SCAMP5	SH3GL1
Description		secretory carrier membrane protein 5	SH3 domain containing GRB2 like 1, endophilin A2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Plasma Membrane Integral Component Of Membrane Synaptic Vesicle Membrane Trans-Golgi Network Membrane Recycling Endosome Membrane	Podosome Cytoplasm Cytosol Early Endosome Membrane Cell Projection Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Presynapse Glutamatergic Synapse Postsynaptic Density, Intracellular Component
	Molecular Function	Protein Binding Protein-containing Complex Binding	Protein Binding Protein C-terminus Binding Lipid Binding SH3 Domain Binding Phosphatase Binding Beta-1 Adrenergic Receptor Binding Identical Protein Binding Transmembrane Transporter Binding Cadherin Binding GTPase Binding
	Biological Process	Positive Regulation Of Cytokine Production Exocytosis Protein Transport Response To Endoplasmic Reticulum Stress Negative Regulation Of Endocytosis Positive Regulation Of Calcium Ion-dependent Exocytosis	Signal Transduction Central Nervous System Development Synaptic Vesicle Uncoating Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Synaptic Vesicle Endocytosis
Pathways			EGFR downregulation Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell
Drugs
Diseases
GWAS		Blood trace element (Zn levels) ( 23720494) Caffeine consumption ( 21490707) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) LDL cholesterol ( 30275531) Mean corpuscular volume ( 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Systemic lupus erythematosus ( 26502338) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Hematocrit ( 32888494) Red cell distribution width ( 32888494)
Interacting Genes		23 interacting genes: AQP6 ARFIP2 CERS4 CREB3 DNAJC5 FATE1 GDNF HSD17B13 MUC1 PAXIP1 PIGP PITPNC1 PLAU SGPL1 SH3GL1 SHISAL1 SLC10A6 SLC9A7 TIMMDC1 TLCD4 TMEM14B TMX2 TTPA	37 interacting genes: ARHGAP1 ARHGAP8 AXIN1 B3GAT1 CCDC50 CMTM5 CREBBP DNM1 DNM1L DPPA4 DPYSL4 FAM102A FBXO32 GPKOW ITCH ITSN2 MAL2 MTA1 NUTM2F PDCD6IP PML PRB3 PRR5-ARHGAP8 PSMB1 PTPRO RHEX SCAMP5 SEPTIN8 SH2D4A SH3D19 SH3GL3 SOCS1 SPG21 STK11 SYNJ1 VPS37C YWHAZ
Entrez ID		192683	6455
HPRD ID		18020	03462
Ensembl ID		ENSG00000198794	ENSG00000141985
Uniprot IDs		A0A0A8K8F5 Q8TAC9	Q6FGM0 Q99961
PDB IDs
Enriched GO Terms of Interacting Partners?
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