SH3GL1 and GPKOW

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SH3GL1	GPKOW
Description		SH3 domain containing GRB2 like 1, endophilin A2	G-patch domain and KOW motifs
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Podosome Cytoplasm Cytosol Early Endosome Membrane Cell Projection Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Presynapse Glutamatergic Synapse Postsynaptic Density, Intracellular Component	Nucleus Nucleoplasm Spliceosomal Complex
	Molecular Function	Protein Binding Protein C-terminus Binding Lipid Binding SH3 Domain Binding Phosphatase Binding Beta-1 Adrenergic Receptor Binding Identical Protein Binding Transmembrane Transporter Binding Cadherin Binding GTPase Binding	RNA Binding Protein Binding
	Biological Process	Signal Transduction Central Nervous System Development Synaptic Vesicle Uncoating Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Synaptic Vesicle Endocytosis	MRNA Splicing, Via Spliceosome
Pathways		EGFR downregulation Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Hematocrit ( 32888494) Red cell distribution width ( 32888494)
Interacting Genes		37 interacting genes: ARHGAP1 ARHGAP8 AXIN1 B3GAT1 CCDC50 CMTM5 CREBBP DNM1 DNM1L DPPA4 DPYSL4 FAM102A FBXO32 GPKOW ITCH ITSN2 MAL2 MTA1 NUTM2F PDCD6IP PML PRB3 PRR5-ARHGAP8 PSMB1 PTPRO RHEX SCAMP5 SEPTIN8 SH2D4A SH3D19 SH3GL3 SOCS1 SPG21 STK11 SYNJ1 VPS37C YWHAZ	48 interacting genes: APP ARMCX1 BUD13 CCDC57 CNKSR3 DDIT4L EFHC2 FBXO7 GMPPA GOLGA2 GSTM5 HOOK2 HSF2BP IKBKG KANK2 LNX1 LRP2BP LZTS1 MAD1L1 MEOX2 MESD MID2 MTUS2 NINL OGT PHF1 PIBF1 PICK1 POLR2G PPP1CA PRKAR1B PRPF4 PRPF8 REL ROPN1 SH3GL1 SORBS3 SPDYE4 TCEA1 TCEA2 TRAF2 TRIM23 TRIM27 VPS52 WDR77 WDR83 ZMYND12 ZRANB1
Entrez ID		6455	27238
HPRD ID		03462	06737
Ensembl ID		ENSG00000141985	ENSG00000068394
Uniprot IDs		Q6FGM0 Q99961	Q92917
PDB IDs
Enriched GO Terms of Interacting Partners?
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