DLG3 and KIF1B

Number of citations of the paper that reports this interaction (PubMedID 16637659)
29

Data Source:
HPRD (in vitro)

		DLG3	KIF1B
Description		discs large MAGUK scaffold protein 3	kinesin family member 1B
Image
GO Annotations	Cellular Component	Extracellular Space Cytosol Plasma Membrane Bicellular Tight Junction Basolateral Plasma Membrane Cell Junction Growth Cone AMPA Glutamate Receptor Complex Neuronal Cell Body Dendritic Shaft Glutamatergic Synapse Postsynaptic Density, Intracellular Component	Mitochondrion Kinesin Complex Microtubule Microtubule Associated Complex Synaptic Vesicle Axon Dendrite Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Neuron Projection Axon Cytoplasm
	Molecular Function	Protein Binding Protein C-terminus Binding Kinase Binding Phosphatase Binding Protein Phosphatase Binding PDZ Domain Binding Ubiquitin Protein Ligase Binding Ionotropic Glutamate Receptor Binding Structural Constituent Of Postsynaptic Density	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding Plus-end-directed Microtubule Motor Activity ATP Hydrolysis Activity Kinesin Binding
	Biological Process	Establishment Of Planar Polarity Negative Regulation Of Cell Population Proliferation Embryo Development Receptor Clustering Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Protein Tyrosine Kinase Activity Receptor Localization To Synapse Cell-cell Adhesion Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Maintenance Of Postsynaptic Density Structure	Apoptotic Process Microtubule-based Movement Neuron-neuron Synaptic Transmission Neuromuscular Synaptic Transmission Anterograde Axonal Transport Vesicle-mediated Transport Cytoskeleton-dependent Intracellular Transport
Pathways		Unblocking of NMDA receptors, glutamate binding and activation Unblocking of NMDA receptors, glutamate binding and activation Ras activation upon Ca2+ influx through NMDA receptor NrCAM interactions Activation of Ca-permeable Kainate Receptor RAF/MAP kinase cascade Neurexins and neuroligins Neurexins and neuroligins Synaptic adhesion-like molecules Assembly and cell surface presentation of NMDA receptors Negative regulation of NMDA receptor-mediated neuronal transmission Long-term potentiation	COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Mean platelet volume ( 32888494)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Hand grip strength ( 29691431) Hematocrit ( 27863252) Hepatitis B virus-related hepatocellular carcinoma ( 29246937) Hepatocellular carcinoma ( 20676096) Hip circumference adjusted for BMI ( 34021172) Lateral orbital frontal cortex volume ( 31530798) Mean platelet volume ( 22139419 32888494 27863252) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 18997785) Neutrophil count ( 32888494) Platelet count ( 32888494) Virologic severity in Herpes simplex virus type 2 infection ( 29535370) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 34021172) White blood cell count ( 32888494)
Interacting Genes		49 interacting genes: ABCA1 ADGRL1 APC ATP2B4 CACNG2 CALM1 CNKSR2 CRIPT DHRS11 DLG1 DLG4 DLGAP1 DLGAP2 DLGAP3 DLGAP4 EIF4H ERBB4 EXOC4 EXOC7 GDA GLS2 GRIK2 GRIN1 GRIN2A GRIN2B GRIN2C GUCY1A2 KCNA4 KCNJ12 KCNJ2 KDELR1 KHDRBS1 KIF1B LIN7A LRP2 MAPK12 NLGN1 NLGN2 NLGN3 OGT OSBP2 PLEKHA2 PTK2B RPS8 SCN4A SCN5A SEMA4C SYNGAP1 VTN	23 interacting genes: ARHGAP1 BRCA1 CALM1 CHP1 CLIP4 CPEB1 DLG1 DLG2 DLG3 DLG4 DYSF EEF1A1 GIPC1 KAZN LAMTOR5 PATJ PGM1 POMP SIAH1 SNTA1 STARD13 TRIM55 YWHAG
Entrez ID		1741	23095
HPRD ID		02177	05818
Ensembl ID		ENSG00000082458	ENSG00000054523
Uniprot IDs		Q59FY1 Q92796	O60333
PDB IDs		1UM7 2FE5 2I1N	2EH0
Enriched GO Terms of Interacting Partners?
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