USP54 and COMTD1

		USP54	COMTD1
Description		ubiquitin specific peptidase 54	catechol-O-methyltransferase domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component		Integral Component Of Membrane
	Molecular Function	Thiol-dependent Deubiquitinase Protein Binding	Protein Binding O-methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity
	Biological Process	Protein Deubiquitination	Methylation
Pathways
Drugs			S-adenosyl-L-homocysteine Sinapoyl coenzyme A Feruloyl Coenzyme A
Diseases
GWAS		Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)	Breast size ( 22747683) Lung function (FVC) ( 30061609)
Interacting Genes		100 interacting genes: ANKRD11 ANKS1A ARID5B ARMC7 ATN1 ATXN1 ATXN1L ATXN7L2 BFSP2 BHLHE40 CARD10 CCDC13 CCDC24 CCNK CDC23 CDK19 CFAP70 CHCHD2 CHERP CHMP1B CHMP2A CHMP2B CHMP4C COMTD1 CSTF2 CYSRT1 DMRT3 DOK6 DTX2 EIF4E2 EPM2AIP1 EXOC8 FAM124B FAM149B1 FBXO17 FNDC3B FOXI1 FUT11 GCM2 HGS HK1 HNF1B HNRNPF HOXC8 IGFN1 INSC KCTD9 LMO3 LNX1 MED25 MID2 MSS51 MSX2 NUDT22 NXT2 OIP5 OTX1 PCSK5 PHF1 PLA2G6 PLAC8 PLCD1 PLEKHN1 POLR1C PRDM6 PRKAB2 PRR35 QRICH1 RACK1 RAMAC RBPMS2 RHOBTB3 RNF208 SAMD8 SEC24A SHARPIN SHC3 SMARCD1 SMYD1 SNRPB SS18L1 STK16 TBX6 TCEA2 TEKT5 TENT5B TFAP2D TLE5 TNS2 TOLLIP TSEN15 TSSK3 TTC19 TTYH1 UBC USP2 VENTX ZCCHC14 ZNF148 ZNF76	4 interacting genes: PAXIP1 UBQLN1 UPF2 USP54
Entrez ID		159195	118881
HPRD ID		15641	08678
Ensembl ID		ENSG00000166348	ENSG00000165644
Uniprot IDs		B7Z7X1 Q70EL1	Q86VU5
PDB IDs			2AVD
Enriched GO Terms of Interacting Partners?
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