USP54 and CHERP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		USP54	CHERP
Description		ubiquitin specific peptidase 54	calcium homeostasis endoplasmic reticulum protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleoplasm Cytoplasm Membrane Sarcoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Thiol-dependent Deubiquitinase Protein Binding	RNA Binding Protein Binding Transmembrane Transporter Binding
	Biological Process	Protein Deubiquitination	RNA Processing Cellular Calcium Ion Homeostasis Nervous System Development Negative Regulation Of Cell Population Proliferation Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		100 interacting genes: ANKRD11 ANKS1A ARID5B ARMC7 ATN1 ATXN1 ATXN1L ATXN7L2 BFSP2 BHLHE40 CARD10 CCDC13 CCDC24 CCNK CDC23 CDK19 CFAP70 CHCHD2 CHERP CHMP1B CHMP2A CHMP2B CHMP4C COMTD1 CSTF2 CYSRT1 DMRT3 DOK6 DTX2 EIF4E2 EPM2AIP1 EXOC8 FAM124B FAM149B1 FBXO17 FNDC3B FOXI1 FUT11 GCM2 HGS HK1 HNF1B HNRNPF HOXC8 IGFN1 INSC KCTD9 LMO3 LNX1 MED25 MID2 MSS51 MSX2 NUDT22 NXT2 OIP5 OTX1 PCSK5 PHF1 PLA2G6 PLAC8 PLCD1 PLEKHN1 POLR1C PRDM6 PRKAB2 PRR35 QRICH1 RACK1 RAMAC RBPMS2 RHOBTB3 RNF208 SAMD8 SEC24A SHARPIN SHC3 SMARCD1 SMYD1 SNRPB SS18L1 STK16 TBX6 TCEA2 TEKT5 TENT5B TFAP2D TLE5 TNS2 TOLLIP TSEN15 TSSK3 TTC19 TTYH1 UBC USP2 VENTX ZCCHC14 ZNF148 ZNF76	49 interacting genes: ADAMTSL4 AGGF1 APBB1 ARGLU1 C1orf94 CCAR1 CLK3 EWSR1 FASTK FIGN FRA10AC1 HNRNPH3 KRTAP11-1 LASP1 LUC7L MAD1L1 MAGED1 MIR106B MIR200C MIR363 MIRLET7A2 MIRLET7C MIRLET7D MIRLET7E MIRLET7G MIRLET7I PPIL4 PRPF38A PRPF40A RACK1 RBFOX2 RBM23 RBM39 RBM7 RNPS1 SART1 SAXO1 SF3B4 SNRNP27 SNRNP70 SORBS3 SRPK1 SRPK2 TLE3 TTC14 U2AF1 U2AF2 USP54 WBP4
Entrez ID		159195	10523
HPRD ID		15641	13051
Ensembl ID		ENSG00000166348	ENSG00000085872
Uniprot IDs		B7Z7X1 Q70EL1	Q8IWX8
PDB IDs
Enriched GO Terms of Interacting Partners?
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