ADRB3 and UBXN8

		ADRB3	UBXN8
Description		adrenoceptor beta 3	UBX domain protein 8
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex	Ubiquitin Ligase Complex Nucleoplasm Nucleolus Endoplasmic Reticulum Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	G Protein-coupled Receptor Activity Beta-adrenergic Receptor Activity Protein Binding Beta3-adrenergic Receptor Activity Protein Homodimerization Activity Epinephrine Binding Norepinephrine Binding	Protein Binding Protein-macromolecule Adaptor Activity
	Biological Process	Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Desensitization Of G Protein-coupled Receptor Signaling Pathway By Arrestin Carbohydrate Metabolic Process Generation Of Precursor Metabolites And Energy Energy Reserve Metabolic Process Receptor-mediated Endocytosis G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Positive Regulation Of MAPK Cascade Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Positive Regulation Of Cold-induced Thermogenesis	Single Fertilization Ubiquitin-dependent ERAD Pathway
Pathways		Adrenoceptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs		Amphetamine Bethanidine Olanzapine Norepinephrine Nortriptyline Propranolol Paroxetine Trimipramine Cryptenamine Alprenolol Terbutaline Salmeterol Pindolol Formoterol Salbutamol Ergoloid mesylate Isoprenaline Arbutamine Amiodarone Fenoterol Ephedra sinica root Mephentermine Clenbuterol Oxprenolol Celiprolol Nebivolol Amibegron Solabegron Droxidopa Bufuralol Bopindolol Bupranolol Mirabegron Racepinephrine Dihydroergocornine DL-Methylephedrine Dihydroergocristine Vibegron
Diseases
GWAS
Interacting Genes		6 interacting genes: ADRB2 GNAS IDO1 SRC UBXN8 WRN	13 interacting genes: ADRB3 AQP6 C8orf86 DCTN6 GJA8 HSD17B13 MEOX2 PGRMC2 RBPMS SFRP1 SPCS1 TMEM14B WRN
Entrez ID		155	7993
HPRD ID		00188	03692
Ensembl ID		ENSG00000188778	ENSG00000104691
Uniprot IDs		A8KAG8 P13945	B4DKK1 O00124
PDB IDs		2CDW
Enriched GO Terms of Interacting Partners?
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