CREB3L4 and GET3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CREB3L4	GET3
Description		cAMP responsive element binding protein 3 like 4	guided entry of tail-anchored proteins factor 3, ATPase
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Chromatin Nucleus Nucleoplasm Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Integral Component Of Membrane Nuclear Membrane	Nucleoplasm Nucleolus Cytoplasm GET Complex Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding CAMP Response Element Binding Sequence-specific Double-stranded DNA Binding	Protein Binding ATP Binding Arsenite Transmembrane Transporter Activity Hydrolase Activity ATP Hydrolysis Activity Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Spermatogenesis Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Transcription By RNA Polymerase II	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Arsenite Transport Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways		CREB3 factors activate genes	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs			ATP
Diseases
GWAS		Age at first birth ( 27798627) Blood protein levels ( 30072576 29875488) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Empathy quotient ( 29527006) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		5 interacting genes: GANAB GET3 LRRC4C SLC19A3 SOX9	41 interacting genes: AGR2 APLN ASPH CACNA1A CAMLG CREB3L4 EMSY FAM209A FKBP7 GET4 GOLM1 GPX7 GPX8 HILPDA IGFBP6 KCNE4 KCNE5 LDLRAD4 PDIA6 PEX14 PFDN1 PGRMC1 PGRMC2 PRB3 PRR4 RHEX SEC61A1 SEC61B SMIM19 SPP1 STATH STX5 SYPL2 TK1 TMEM154 TMEM51 TMX1 TTR VAMP2 VWC2 WFDC3
Entrez ID		148327	439
HPRD ID		06323	03555
Ensembl ID		ENSG00000143578	ENSG00000198356
Uniprot IDs		Q8TEY5	O43681
PDB IDs			6SO5
Enriched GO Terms of Interacting Partners?
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