GET3 and SYPL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GET3	SYPL2
Description		guided entry of tail-anchored proteins factor 3, ATPase	synaptophysin like 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm GET Complex Extracellular Exosome	Integral Component Of Membrane Synaptic Vesicle Membrane
	Molecular Function	Protein Binding ATP Binding Arsenite Transmembrane Transporter Activity Hydrolase Activity ATP Hydrolysis Activity Metal Ion Binding
	Biological Process	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Arsenite Transport Tail-anchored Membrane Protein Insertion Into ER Membrane	Cellular Calcium Ion Homeostasis Heart Development Substantia Nigra Development T-tubule Organization
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs		ATP
Diseases
GWAS			Body mass index ( 29273807) Chronic kidney disease ( 20383146) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Estimated glomerular filtration rate ( 31152163 31015462) Glomerular filtration rate (creatinine) ( 28452372 26831199) Major depressive disorder ( 20125088)
Interacting Genes		41 interacting genes: AGR2 APLN ASPH CACNA1A CAMLG CREB3L4 EMSY FAM209A FKBP7 GET4 GOLM1 GPX7 GPX8 HILPDA IGFBP6 KCNE4 KCNE5 LDLRAD4 PDIA6 PEX14 PFDN1 PGRMC1 PGRMC2 PRB3 PRR4 RHEX SEC61A1 SEC61B SMIM19 SPP1 STATH STX5 SYPL2 TK1 TMEM154 TMEM51 TMX1 TTR VAMP2 VWC2 WFDC3	6 interacting genes: ATP13A1 GET3 PLLP SLC38A7 SLC41A1 YIPF2
Entrez ID		439	284612
HPRD ID		03555	17478
Ensembl ID		ENSG00000198356	ENSG00000143028
Uniprot IDs		O43681	B4DYR7 Q5VXT5
PDB IDs		6SO5
Enriched GO Terms of Interacting Partners?
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