STK35 and OSBPL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		STK35	OSBPL3
Description		serine/threonine kinase 35	oxysterol binding protein like 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Nuclear Body	Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Nuclear Membrane Filopodium Tip Intracellular Membrane-bounded Organelle Perinuclear Endoplasmic Reticulum
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	Protein Binding Sterol Transporter Activity Cholesterol Binding Sterol Binding
	Biological Process	Protein Phosphorylation Meiotic Cell Cycle	Bile Acid Biosynthetic Process Sterol Transport
Pathways			Synthesis of bile acids and bile salts
Drugs		Fostamatinib
Diseases
GWAS		Adult body size ( 32376654) Basal cell carcinoma ( 33549134) Early spontaneous preterm birth ( 31194736) Immune response to measles-mumps-rubella vaccine ( 24811271) Keratoconus ( 33649486) Plateletcrit ( 32888494) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172)	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Pursuit maintenance gain ( 29064472) Sulfasalazine-induced agranulocytosis ( 28762467)
Interacting Genes		6 interacting genes: BMPR1B OSBPL3 PDLIM1 SMAD4 SMURF1 TGFBR1	26 interacting genes: ACSM1 BYSL FAM161A GABARAPL1 GABARAPL2 LNX1 MCRS1 PALS2 PLK4 PRPF18 PRPF3 RALGPS2 RPL11 STK35 SYTL4 TCEA2 TCEANC TRAF3IP3 WT1 YWHAB YWHAG ZBTB16 ZNF48 ZNF497 ZNF648 ZNF835
Entrez ID		140901	26031
HPRD ID		11612	09474
Ensembl ID		ENSG00000125834	ENSG00000070882
Uniprot IDs		Q8TDR2	Q9H4L5
PDB IDs			7CYZ
Enriched GO Terms of Interacting Partners?
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