GPR151 and BCL2L2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GPR151	BCL2L2
Description		G protein-coupled receptor 151	BCL2 like 2
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane	Mitochondrial Outer Membrane Cytosol Bcl-2 Family Protein Complex
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Identical Protein Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Protein Heterodimerization Activity BH Domain Binding Disordered Domain Specific Binding
	Biological Process	Response To Ischemia G Protein-coupled Receptor Signaling Pathway Response To Acidic PH Positive Regulation Of Immune Response	Response To Ischemia Spermatogenesis Brain Development Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Mitochondrial Membrane Permeability Negative Regulation Of Apoptotic Process Sertoli Cell Proliferation Cellular Response To Estradiol Stimulus Negative Regulation Of Release Of Cytochrome C From Mitochondria Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Cellular Response To Amyloid-beta Cellular Response To Glycine Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs			Navitoclax
Diseases
GWAS		Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	Height ( 28552196) Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		42 interacting genes: APOD AQP6 ARL6IP1 BCL2L2 C1GALT1 CD300C CDIPT CERS4 CGRRF1 CREB3L1 CYBC1 EFNA5 ERGIC3 FAM209A GAL GJA8 GPR152 GPX8 IGFBP5 KEAP1 LAT MANBAL NRM PGRMC2 PLP2 SACM1L SCN3B SHISAL1 SLC10A1 SLC10A6 SLC18A1 SLC18A2 SLC41A2 SSMEM1 STX8 TIMMDC1 TMBIM6 TMEM179B TMEM239 TMEM31 TRARG1 UNC93A	53 interacting genes: ANKS6 APOC1 APOC2 APOC4 ATP5PF BAD BAK1 BAX BBC3 BCL2L11 BHLHA9 BID BIK BMF BNIP3 BNIP5 C10orf67 CD79A CHODL CIDEB CISD2 CLDN7 ERVFRD-1 FATE1 G0S2 GORAB GPR151 GPX8 HRK KASH5 KCNJ6 LMNA LRRIQ1 MGST2 MUC1 PANX1 PPP1CA PSCA RHBDD2 S100B SAR1A SGPL1 SLC35C2 SLC35E3 SLC39A2 SLC39A6 STOM SUSD3 TCF4 TEX11 TMEM139 TMX1 TP53
Entrez ID		134391	599
HPRD ID		17065	03569
Ensembl ID		ENSG00000173250	ENSG00000129473
Uniprot IDs		Q8TDV0	Q92843
PDB IDs			1MK3 1O0L 1ZY3 2Y6W 4CIM
Enriched GO Terms of Interacting Partners?
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