BCL2L2 and CIDEB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		BCL2L2	CIDEB
Description		BCL2 like 2	cell death inducing DFFA like effector b
Image
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Cytosol Bcl-2 Family Protein Complex	Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Protein Heterodimerization Activity BH Domain Binding Disordered Domain Specific Binding	Protein Binding Identical Protein Binding
	Biological Process	Response To Ischemia Spermatogenesis Brain Development Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Mitochondrial Membrane Permeability Negative Regulation Of Apoptotic Process Sertoli Cell Proliferation Cellular Response To Estradiol Stimulus Negative Regulation Of Release Of Cytochrome C From Mitochondria Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Cellular Response To Amyloid-beta Cellular Response To Glycine Negative Regulation Of Intrinsic Apoptotic Signaling Pathway	Apoptotic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Cell Death Response To Nutrient Levels Bile Acid Signaling Pathway Regulation Of Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria Execution Phase Of Apoptosis Activation Of Cysteine-type Endopeptidase Activity
Pathways
Drugs		Navitoclax
Diseases
GWAS		Height ( 28552196) Hip circumference adjusted for BMI ( 34021172)	Anorectal malformation ( 31136621) Height ( 28552196) Parent of origin effect on language impairment (paternal) ( 24571439)
Interacting Genes		53 interacting genes: ANKS6 APOC1 APOC2 APOC4 ATP5PF BAD BAK1 BAX BBC3 BCL2L11 BHLHA9 BID BIK BMF BNIP3 BNIP5 C10orf67 CD79A CHODL CIDEB CISD2 CLDN7 ERVFRD-1 FATE1 G0S2 GORAB GPR151 GPX8 HRK KASH5 KCNJ6 LMNA LRRIQ1 MGST2 MUC1 PANX1 PPP1CA PSCA RHBDD2 S100B SAR1A SGPL1 SLC35C2 SLC35E3 SLC39A2 SLC39A6 STOM SUSD3 TCF4 TEX11 TMEM139 TMX1 TP53	68 interacting genes: ABHD16A AFG1L APOC1 ARL8B ATP5ME ATP5MJ BCL2L2 C5orf38 CAND2 CIDEA CLCN1 CMPK1 COL10A1 COL8A1 COX7C DFFA DFFB DHRSX DNAJA3 FAM218A FAM47E-STBD1 FKBP8 FOXD4L3 FUNDC2 GCSH GNB3 GPAM H4C7 HAPLN2 HCCS HIGD1C MEST MICOS10 MPC2 MRPL36 MRPL57 MTERF4 NAALAD2 NDRG4 NFU1 NME4 PBX3 PDHX PGLYRP3 PISD PPIF RAMP2 RHBDD2 ROMO1 RTP5 SAA2 SAA4 SAR1B SCO1 SCO2 SDHAF1 SFXN1 SMARCC1 SPG21 TAOK2 TBX2 TEX44 THBD TIMM17B TMEM14B TPRG1 TSR1 UFSP1
Entrez ID		599	27141
HPRD ID		03569	11981
Ensembl ID		ENSG00000129473	ENSG00000136305
Uniprot IDs		Q92843	Q9UHD4
PDB IDs		1MK3 1O0L 1ZY3 2Y6W 4CIM	1D4B
Enriched GO Terms of Interacting Partners?
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