PRXL2B and COPS3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PRXL2B	COPS3
Description		peroxiredoxin like 2B	COP9 signalosome subunit 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cytosol Myelin Sheath Extracellular Exosome	Nucleoplasm Cytoplasm Cytosol COP9 Signalosome
	Molecular Function	Protein Binding Antioxidant Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Prostaglandin-F Synthase Activity	Protein Binding
	Biological Process	Prostaglandin Biosynthetic Process Cellular Oxidant Detoxification	Protein Deneddylation In Utero Embryonic Development Ubiquitin-dependent Protein Catabolic Process Signal Transduction Response To Light Stimulus
Pathways		Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation
Drugs
Diseases
GWAS			Alanine aminotransferase levels ( 33547301) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil percentage of white cells ( 32888494) Reticulocyte count ( 32888494)
Interacting Genes		4 interacting genes: COPS3 PDPK1 TCP11L1 TNFSF11	32 interacting genes: ARAF ARF4 C17orf75 CEBPE COPS2 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8 COPS9 CSNK2A1 CSNK2B CUL5 FLAD1 FRS3 GPS1 IKBKB IKBKG IL1RN IRF5 ITGB2 KRT80 LRP2BP MCPH1 MLF1 NABP1 PRXL2B RAF1 SOS1 TP53
Entrez ID		127281	8533
HPRD ID		14513	07262
Ensembl ID		ENSG00000157870	ENSG00000141030
Uniprot IDs		A0A0A0MRV4 A0A0A0MT35 A0A2P0CTB1 A0A2P0CU24 Q8TBF2	B4DN01 Q9UNS2
PDB IDs			4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N
Enriched GO Terms of Interacting Partners?
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