CNR2 and TMEM19

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CNR2	TMEM19
Description		cannabinoid receptor 2	transmembrane protein 19
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Dendrite Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Perikaryon	Membrane Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Activity Cannabinoid Receptor Activity Protein Binding	Protein Binding
	Biological Process	Response To Amphetamine Inflammatory Response Immune Response G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Metabolic Process Sensory Perception Of Pain Leukocyte Chemotaxis Negative Regulation Of Synaptic Transmission, GABAergic Response To Lipopolysaccharide Negative Regulation Of Mast Cell Activation Cannabinoid Signaling Pathway Negative Regulation Of Action Potential Negative Regulation Of Inflammatory Response Negative Regulation Of Nitric-oxide Synthase Activity
Pathways		Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events
Drugs		Dronabinol Nabilone Ricinoleic Acid Lasofoxifene Cannabidiol Tetrahydrocannabivarin Medical Cannabis Nabiximols
Diseases
GWAS		Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular volume ( 32888494) Multiple sclerosis ( 31604244) Psychotic experience (distressing) ( 31553412)	Nonsyndromic cleft lip with cleft palate ( 28232668)
Interacting Genes		24 interacting genes: ADAM21 ADIPOQ AGPAT4 CCL4 COMT FXYD3 GNA15 MUC15 NRM PEDS1-UBE2V1 RFT1 SELENOK SLC35E4 SLC39A2 TMEM19 TMEM203 TMEM242 TMEM60 TMEM86A TMPPE TSPO2 YIPF1 YIPF4 YIPF6	38 interacting genes: APOA5 AQP6 BSCL2 C10orf67 CD3G CD79A CNR2 CPLX4 CREB3 CREB3L1 ELOVL4 FAM210B FCER1G GJB1 GORAB GPR42 GPRC5D GPX8 HSD17B13 KASH5 LDAF1 LEPROTL1 LY6E MC4R MFSD14B PGRMC2 PIGP PTGES REEP4 RNF185 SERTM1 SLC7A1 SUSD6 TEX29 TLCD4 TMEM139 TMEM14B TMEM45A
Entrez ID		1269	55266
HPRD ID		05444	15530
Ensembl ID		ENSG00000188822	ENSG00000139291
Uniprot IDs		A0A024RAH7 P34972	A0A024RBA1 Q96HH6
PDB IDs		2KI9 5ZTY 6KPC 6KPF 6PT0
Enriched GO Terms of Interacting Partners?
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