TAGAP and RSPH3

		TAGAP	RSPH3
Description		T cell activation RhoGTPase activating protein	radial spoke head 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Cytoplasm Cytoskeleton Cilium
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding	Protein Binding
	Biological Process	Signal Transduction Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Autoimmune traits (pleiotropy) ( 30572963) Bladder cancer (smoking interaction) ( 24662972) Celiac disease ( 22057235 20190752 25920553 24999842 30572963 18311140) Celiac disease and Rheumatoid arthritis ( 26546613) Crohn's disease ( 21102463 23128233) Crohn's disease and celiac disease ( 21298027) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Lipoprotein (a) - cholesterol levels ( 25575512) Lipoprotein (a) levels ( 26377243) Multiple sclerosis ( 31604244 22190364 24076602 21833088) Psoriasis ( 23143594) Rheumatoid arthritis ( 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) Systemic lupus erythematosus ( 28714469) Type 1 diabetes ( 34127860)	Attention deficit hyperactivity disorder ( 32279069) Bladder cancer (smoking interaction) ( 24662972) Celiac disease ( 25920553) Lipoprotein (a) levels ( 26377243) Prepulse inhibition of the startle response ( 31596458) Systemic lupus erythematosus ( 28714469)
Interacting Genes		4 interacting genes: HSF2BP OSTCP1 RSPH3 TMEM181	9 interacting genes: APP DPY30 FAM124B HSPB1 MLH1 PRKAR1A ROPN1L RSPH14 TAGAP
Entrez ID		117289	83861
HPRD ID		18143	15279
Ensembl ID		ENSG00000164691	ENSG00000130363
Uniprot IDs		Q8N103	Q86UC2
PDB IDs
Enriched GO Terms of Interacting Partners?
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