TAGAP and TMEM181

		TAGAP	TMEM181
Description		T cell activation RhoGTPase activating protein	transmembrane protein 181
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Integral Component Of Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding	Toxic Substance Binding
	Biological Process	Signal Transduction Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Autoimmune traits (pleiotropy) ( 30572963) Bladder cancer (smoking interaction) ( 24662972) Celiac disease ( 22057235 20190752 25920553 24999842 30572963 18311140) Celiac disease and Rheumatoid arthritis ( 26546613) Crohn's disease ( 21102463 23128233) Crohn's disease and celiac disease ( 21298027) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Lipoprotein (a) - cholesterol levels ( 25575512) Lipoprotein (a) levels ( 26377243) Multiple sclerosis ( 31604244 22190364 24076602 21833088) Psoriasis ( 23143594) Rheumatoid arthritis ( 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) Systemic lupus erythematosus ( 28714469) Type 1 diabetes ( 34127860)	Glaucoma ( 31959993) Glaucoma (primary open-angle) ( 29891935) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Intraocular pressure ( 29785010 31959993)
Interacting Genes		4 interacting genes: HSF2BP OSTCP1 RSPH3 TMEM181	1 interacting genes: TAGAP
Entrez ID		117289	57583
HPRD ID		18143	19623
Ensembl ID		ENSG00000164691	ENSG00000146433
Uniprot IDs		Q8N103	Q9P2C4
PDB IDs
Enriched GO Terms of Interacting Partners?
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