GALNT15 and IL27RA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GALNT15	IL27RA
Description		polypeptide N-acetylgalactosaminyltransferase 15	interleukin 27 receptor subunit alpha
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Membrane Transport Vesicle	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Interleukin-12 Receptor Complex Receptor Complex Interleukin-23 Receptor Complex
	Molecular Function	Polypeptide N-acetylgalactosaminyltransferase Activity Protein Binding Carbohydrate Binding Metal Ion Binding	Transmembrane Signaling Receptor Activity Cytokine Receptor Activity Interleukin-12 Receptor Binding Protein Binding Cytokine Binding Interleukin-23 Binding Interleukin-27 Receptor Activity
	Biological Process	O-glycan Processing	Positive Regulation Of T-helper 1 Type Immune Response Negative Regulation Of Type 2 Immune Response Immune Response Cell Surface Receptor Signaling Pathway Cytokine-mediated Signaling Pathway Negative Regulation Of Interleukin-17 Production Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Interferon-gamma Production Positive Regulation Of Activated T Cell Proliferation Regulation Of Isotype Switching To IgG Isotypes Defense Response To Gram-positive Bacterium Interleukin-27-mediated Signaling Pathway Negative Regulation Of T-helper 17 Type Immune Response Negative Regulation Of T Cell Extravasation
Pathways		O-linked glycosylation of mucins	Interleukin-35 Signalling Interleukin-27 signaling Interleukin-27 signaling
Drugs
Diseases
GWAS		Numerical cognitive ability ( 31620175) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	Blood protein levels ( 30072576 29875488) Immune response to measles-mumps-rubella vaccine ( 24811271) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		18 interacting genes: CD200R1 CD79A CISD2 EVI2B FCRL6 FFAR2 FNDC9 GOLM1 IL27RA MR1 MUC1 PDCD1LG2 PDZK1IP1 SLC30A2 SLC7A1 SPSB2 SYNPR TMEM179B	13 interacting genes: BRICD5 CLDN2 DEFB121 DERL3 EBI3 GALNT15 GDF15 IL27 MAPK8 MFSD5 SLC41A2 STAT1 YIPF6
Entrez ID		117248	9466
HPRD ID		13563	09247
Ensembl ID		ENSG00000131386	ENSG00000104998
Uniprot IDs		B3KT16 C9JGI4 Q4G146 Q8N3T1	Q6UWB1
PDB IDs
Enriched GO Terms of Interacting Partners?
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