RAB31 and MPP3

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		RAB31	MPP3
Description		RAB31, member RAS oncogene family	MAGUK p55 scaffold protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Phagocytic Cup Early Endosome Cytosol Plasma Membrane Endomembrane System Secretory Granule Membrane Early Endosome Membrane Trans-Golgi Network Membrane Early Phagosome Membrane Phagocytic Vesicle
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding	Protein Binding PDZ Domain Binding
	Biological Process	Intracellular Protein Transport Receptor Internalization Cellular Response To Insulin Stimulus Golgi To Plasma Membrane Protein Transport Regulated Exocytosis Positive Regulation Of Phagocytosis, Engulfment Phagosome Maturation
Pathways		Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 27089180) Basophil count ( 32888494) Blood pressure (age interaction) ( 24954895) Bone fracture in osteoporosis ( 28580392) Dupuytren's disease ( 28886342) Lung adenocarcinoma ( 28604730)	HDL cholesterol levels ( 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) Triglycerides ( 24097068)
Interacting Genes		7 interacting genes: ALS2CL EEA1 EGFR IRAK1 MAPK6 MPP3 OCRL	40 interacting genes: APP ARL2BP BTBD1 CADM1 CCDC137 CRABP1 ERBIN EZR FAM171B FBXO7 GNG7 HAP1 HSH2D IDUA INSM1 KBTBD4 KRTAP10-3 L3MBTL2 LIN7A LIN7B LIN7C MCM2 MDH1 NOA1 PKNOX1 PLK2 RAB31 RPS2 RRAGC SCN2A SF3B3 SNTG2 SRPK2 TBK1 TIRAP TMEM37 TRAF2 TRIM41 ZNF655 ZPR1
Entrez ID		11031	4356
HPRD ID		05751	03069
Ensembl ID		ENSG00000168461	ENSG00000161647
Uniprot IDs		Q13636	D3DX46 Q13368
PDB IDs		2FG5
Enriched GO Terms of Interacting Partners?
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