MPP3 and RRAGC

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		MPP3	RRAGC
Description		MAGUK p55 scaffold protein 3	Ras related GTP binding C
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Cytoplasm Lysosome Cytosol Intracellular Membrane-bounded Organelle Gtr1-Gtr2 GTPase Complex
	Molecular Function	Protein Binding PDZ Domain Binding	Magnesium Ion Binding GTPase Activity Protein Binding GTP Binding GDP Binding Protein Heterodimerization Activity GTPase Binding
	Biological Process		Transcription, DNA-templated Apoptotic Process Small GTPase Mediated Signal Transduction RNA Splicing Cellular Response To Starvation Regulation Of Autophagy Regulation Of TOR Signaling Positive Regulation Of TOR Signaling Cellular Response To Amino Acid Starvation Cellular Protein Localization Response To Amino Acid Cellular Response To Amino Acid Stimulus Regulation Of TORC1 Signaling
Pathways			Macroautophagy MTOR signalling mTORC1-mediated signalling Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Regulation of PTEN gene transcription Amino acids regulate mTORC1
Drugs
Diseases
GWAS		HDL cholesterol levels ( 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) Triglycerides ( 24097068)	Beard thickness ( 26926045) Blood protein levels ( 28240269)
Interacting Genes		40 interacting genes: APP ARL2BP BTBD1 CADM1 CCDC137 CRABP1 ERBIN EZR FAM171B FBXO7 GNG7 HAP1 HSH2D IDUA INSM1 KBTBD4 KRTAP10-3 L3MBTL2 LIN7A LIN7B LIN7C MCM2 MDH1 NOA1 PKNOX1 PLK2 RAB31 RPS2 RRAGC SCN2A SF3B3 SNTG2 SRPK2 TBK1 TIRAP TMEM37 TRAF2 TRIM41 ZNF655 ZPR1	7 interacting genes: ATXN1L DEPDC5 MPP3 NOL8 RRAGA RRAGB WNT2
Entrez ID		4356	64121
HPRD ID		03069	12198
Ensembl ID		ENSG00000161647	ENSG00000116954
Uniprot IDs		D3DX46 Q13368	B4DQ03 B4DQG4 Q9HB90
PDB IDs			3LLU 6CES 6EHR 6NZD 6S6A 6S6D 6SB0 6SB2 6U62 6ULG 6WJ2 6WJ3
Enriched GO Terms of Interacting Partners?
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