RAB31 and EEA1

Number of citations of the paper that reports this interaction (PubMedID 24644286)
14

Data Source:
BioGRID (pull down)

		RAB31	EEA1
Description		RAB31, member RAS oncogene family	early endosome antigen 1
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GO Annotations	Cellular Component	Phagocytic Cup Early Endosome Cytosol Plasma Membrane Endomembrane System Secretory Granule Membrane Early Endosome Membrane Trans-Golgi Network Membrane Early Phagosome Membrane Phagocytic Vesicle	Cytoplasm Early Endosome Cytosol Serine-pyruvate Aminotransferase Complex Membrane Extrinsic Component Of Plasma Membrane Early Endosome Membrane Axonal Spine Recycling Endosome Extracellular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding	Protein Binding Calmodulin Binding 1-phosphatidylinositol Binding Zinc Ion Binding GTP-dependent Protein Binding Protein Homodimerization Activity
	Biological Process	Intracellular Protein Transport Receptor Internalization Cellular Response To Insulin Stimulus Golgi To Plasma Membrane Protein Transport Regulated Exocytosis Positive Regulation Of Phagocytosis, Engulfment Phagosome Maturation	Endocytosis Vesicle Fusion Synaptic Vesicle To Endosome Fusion Viral RNA Genome Replication Early Endosome To Late Endosome Transport
Pathways		Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Toll Like Receptor 9 (TLR9) Cascade
Drugs			Inositol 1,3-Bisphosphate
Diseases
GWAS		Age at first sexual intercourse ( 27089180) Basophil count ( 32888494) Blood pressure (age interaction) ( 24954895) Bone fracture in osteoporosis ( 28580392) Dupuytren's disease ( 28886342) Lung adenocarcinoma ( 28604730)	Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Sensorimotor dexterity ( 31596458) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Western dietary pattern ( 28644415)
Interacting Genes		7 interacting genes: ALS2CL EEA1 EGFR IRAK1 MAPK6 MPP3 OCRL	13 interacting genes: IGF1R MAPK14 RAB22A RAB31 RAB5A RAB5B RAB5C RRAD STX12 STX6 TOM1 USO1 ZFYVE16
Entrez ID		11031	8411
HPRD ID		05751	05460
Ensembl ID		ENSG00000168461	ENSG00000102189
Uniprot IDs		Q13636	Q15075
PDB IDs		2FG5	1HYI 1HYJ 1JOC 3MJH
Enriched GO Terms of Interacting Partners?
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