LILRB3 and CHRNA1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LILRB3	CHRNA1
Description		leukocyte immunoglobulin like receptor B3	cholinergic receptor nicotinic alpha 1 subunit
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Secretory Granule Membrane	Plasma Membrane Integral Component Of Plasma Membrane Acetylcholine-gated Channel Complex Cell Surface Neuromuscular Junction Neuron Projection Synapse Postsynaptic Membrane Integral Component Of Postsynaptic Specialization Membrane
	Molecular Function	Amyloid-beta Binding Transmembrane Signaling Receptor Activity Protein Binding Inhibitory MHC Class I Receptor Activity Signaling Receptor Activity	Ion Channel Activity Acetylcholine Receptor Activity Acetylcholine-gated Cation-selective Channel Activity Neurotransmitter Receptor Activity Acetylcholine Binding Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process	Adaptive Immune Response Defense Response Cell Surface Receptor Signaling Pathway Cytokine-mediated Signaling Pathway Negative Regulation Of Osteoclast Differentiation	Skeletal Muscle Contraction Cation Transport Signal Transduction Chemical Synaptic Transmission Synaptic Transmission, Cholinergic Neuromuscular Synaptic Transmission Neuromuscular Junction Development Neuronal Action Potential Ion Transmembrane Transport Regulation Of Membrane Potential Muscle Cell Cellular Homeostasis Skeletal Muscle Tissue Growth Nervous System Process Musculoskeletal Movement Neuromuscular Process Excitatory Postsynaptic Potential Neuron Cellular Homeostasis
Pathways			Highly calcium permeable postsynaptic nicotinic acetylcholine receptors Highly calcium permeable nicotinic acetylcholine receptors
Drugs			Lamotrigine Agmatine
Diseases
GWAS		Birth weight ( 31043758) Monocyte count ( 32888494) Takayasu arteritis ( 25604533)	Atrial fibrillation ( 29892015)
Interacting Genes		3 interacting genes: CHRNA1 GRID1 RPL38	5 interacting genes: CHRND CHRNE CHRNG ITGA7 LILRB3
Entrez ID		11025	1134
HPRD ID		11995	00007
Ensembl ID		ENSG00000204577	ENSG00000138435
Uniprot IDs			P02708 Q53SH4
PDB IDs			1Y5P 1Y5T 1Y6C 4ZJS 5HBT
Enriched GO Terms of Interacting Partners?
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