CHRNA1 and CHRNG

Number of citations of the paper that reports this interaction (PubMedID 7695910)
20

Data Source:
HPRD (in vitro)

		CHRNA1	CHRNG
Description		cholinergic receptor nicotinic alpha 1 subunit	cholinergic receptor nicotinic gamma subunit
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Acetylcholine-gated Channel Complex Cell Surface Neuromuscular Junction Neuron Projection Synapse Postsynaptic Membrane Integral Component Of Postsynaptic Specialization Membrane	Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection Synapse Postsynaptic Membrane
	Molecular Function	Ion Channel Activity Acetylcholine Receptor Activity Acetylcholine-gated Cation-selective Channel Activity Neurotransmitter Receptor Activity Acetylcholine Binding Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential	Protein Binding Channel Activity Acetylcholine Receptor Activity Acetylcholine-gated Cation-selective Channel Activity Neurotransmitter Receptor Activity
	Biological Process	Skeletal Muscle Contraction Cation Transport Signal Transduction Chemical Synaptic Transmission Synaptic Transmission, Cholinergic Neuromuscular Synaptic Transmission Neuromuscular Junction Development Neuronal Action Potential Ion Transmembrane Transport Regulation Of Membrane Potential Muscle Cell Cellular Homeostasis Skeletal Muscle Tissue Growth Nervous System Process Musculoskeletal Movement Neuromuscular Process Excitatory Postsynaptic Potential Neuron Cellular Homeostasis	Muscle Contraction Signal Transduction Chemical Synaptic Transmission Synaptic Transmission, Cholinergic Ion Transmembrane Transport Regulation Of Membrane Potential Nervous System Process Excitatory Postsynaptic Potential
Pathways		Highly calcium permeable postsynaptic nicotinic acetylcholine receptors Highly calcium permeable nicotinic acetylcholine receptors	Highly sodium permeable postsynaptic acetylcholine nicotinic receptors
Drugs		Lamotrigine Agmatine
Diseases
GWAS		Atrial fibrillation ( 29892015)	Refractive error ( 23396134 32231278)
Interacting Genes		5 interacting genes: CHRND CHRNE CHRNG ITGA7 LILRB3	21 interacting genes: ADAMTSL4 CHRNA1 CYSRT1 KRT31 KRT34 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP5-9 KRTAP9-3 MDFI MEOX2 NBPF19 NOTCH2NLA SGTA SNX1 SPRY2
Entrez ID		1134	1146
HPRD ID		00007	00009
Ensembl ID		ENSG00000138435	ENSG00000196811
Uniprot IDs		P02708 Q53SH4	A0A6F7YAP6 P07510
PDB IDs		1Y5P 1Y5T 1Y6C 4ZJS 5HBT
Enriched GO Terms of Interacting Partners?
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