PTGES3 and AHSA1

Number of citations of the paper that reports this interaction (PubMedID 22504172)
13

Data Source:
BioGRID (pull down, affinity chromatography technology)

		PTGES3	AHSA1
Description		prostaglandin E synthase 3	activator of HSP90 ATPase activity 1
Image
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm Telomerase Holoenzyme Complex Cytosol Protein-containing Complex Chaperone Complex	Endoplasmic Reticulum Cytosol Extracellular Exosome
	Molecular Function	Telomerase Activity Protein Binding Prostaglandin-E Synthase Activity Unfolded Protein Binding Chaperone Binding Hsp90 Protein Binding DNA Polymerase Binding	ATPase Activator Activity Protein Binding Cadherin Binding Chaperone Binding Hsp90 Protein Binding
	Biological Process	Telomere Maintenance Prostaglandin Biosynthetic Process Glycogen Biosynthetic Process Protein Folding Telomere Maintenance Via Telomerase Signal Transduction Cell Population Proliferation Cyclooxygenase Pathway Positive Regulation Of Phosphorylation Glucocorticoid Receptor Signaling Pathway Skin Development Protein Stabilization Chaperone Cofactor-dependent Protein Refolding Chaperone-mediated Protein Complex Assembly Positive Regulation Of Telomerase Activity Lung Saccule Development Telomerase Holoenzyme Complex Assembly	Protein Folding Positive Regulation Of ATPase Activity Regulation Of Catalytic Activity
Pathways		Synthesis of Prostaglandins (PG) and Thromboxanes (TX) HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand HSF1 activation Attenuation phase Aryl hydrocarbon receptor signalling ESR-mediated signaling Estrogen-dependent gene expression Potential therapeutics for SARS
Drugs		Acetaminophen Grn163l Copper
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Asthma ( 31619474) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 27863252) Liver enzyme levels (alanine transaminase) ( 33972514) Mean platelet volume ( 22139419) Platelet count ( 22139419) Reticulocyte count ( 32888494)
Interacting Genes		29 interacting genes: AHR AHSA1 AIP ARNT CASP3 CASP7 CAV3 CD2AP CDC37 COPG1 COPG2 DNAJB1 DNMT3A EIF2AK2 ERBB3 ESR1 FES GZMB HSF1 HSP90AA1 HSP90AB1 HSPA1A HSPB1 NR3C1 NR3C2 STIP1 SURF1 TERT THRA	9 interacting genes: AKT1 APP CLCN1 EGFR FKBP4 GCH1 HSP90AA1 OGT PTGES3
Entrez ID		10728	10598
HPRD ID		06138	09768
Ensembl ID		ENSG00000110958	ENSG00000100591
Uniprot IDs		A0A024RB32 A0A087WYT3 B3KUY2 Q15185	G3V438 O95433
PDB IDs		1EJF 1LG0	1X53
Enriched GO Terms of Interacting Partners?
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