RHBDD1 and LPCAT2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RHBDD1	LPCAT2
Description		rhomboid domain containing 1	lysophosphatidylcholine acyltransferase 2
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane Mitochondrial Membrane Endoplasmic Reticulum Quality Control Compartment	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Stack Lipid Droplet Plasma Membrane Integral Component Of Membrane
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding	1-acylglycerol-3-phosphate O-acyltransferase Activity Calcium Ion Binding Protein Binding 2-acylglycerol-3-phosphate O-acyltransferase Activity 1-alkenylglycerophosphocholine O-acyltransferase Activity 1-acylglycerophosphocholine O-acyltransferase Activity 1-alkylglycerophosphocholine O-acetyltransferase Activity Plasmalogen Synthase Activity
	Biological Process	Apoptotic Process Positive Regulation Of Protein Processing Membrane Protein Intracellular Domain Proteolysis Cellular Response To Unfolded Protein Cellular Response To UV ERAD Pathway Negative Regulation Of Apoptotic Process Post-translational Protein Modification Spermatid Differentiation Membrane Protein Proteolysis Involved In Retrograde Protein Transport, ER To Cytosol Regulation Of Male Germ Cell Proliferation	Platelet Activating Factor Biosynthetic Process Phosphatidylcholine Acyl-chain Remodeling Membrane Organization
Pathways			Acyl chain remodelling of PC
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Kawasaki disease ( 33692975) Pulmonary function ( 17903307)	Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Thyroid hormone levels ( 23408906)
Interacting Genes		19 interacting genes: CGRRF1 CMTM5 CREB3L1 CTSA DAPK1 FBXO25 GYPC LPCAT2 LRRK2 MFHAS1 NSDHL PLEKHB2 RNF5 SEC22B SLC66A2 TGFA TMEM42 TMEM86B TMIE	8 interacting genes: CREB3 EBP ERGIC3 HSD17B13 KCNJ6 MFSD14B RETREG3 RHBDD1
Entrez ID		84236	54947
HPRD ID		13206	07913
Ensembl ID		ENSG00000144468	ENSG00000087253
Uniprot IDs		Q8TEB9	Q7L5N7
PDB IDs		5EPP
Enriched GO Terms of Interacting Partners?
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