KHDRBS1 and AHI1

Number of citations of the paper that reports this interaction (PubMedID 22745667)
6

Data Source:
BioGRID (unspecified method)

		KHDRBS1	AHI1
Description		KH RNA binding domain containing, signal transduction associated 1	Abelson helper integration site 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Protein-containing Complex Grb2-Sos Complex	Centrosome Centriole Cytosol Cell-cell Junction Adherens Junction Cilium MKS Complex Ciliary Basal Body Non-motile Cilium
	Molecular Function	DNA Binding RNA Binding MRNA Binding Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding Protein Domain Specific Binding Signaling Adaptor Activity SH2 Domain Binding Identical Protein Binding Protein-containing Complex Binding Protein Tyrosine Kinase Binding	Protein Binding Identical Protein Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Spermatogenesis Regulation Of Protein Stability Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Translational Initiation Regulation Of RNA Export From Nucleus Positive Regulation Of RNA Export From Nucleus Regulation Of MRNA Splicing, Via Spliceosome T Cell Receptor Signaling Pathway	Morphogenesis Of A Polarized Epithelium Heart Looping Positive Regulation Of Receptor Internalization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Central Nervous System Development Retina Layer Formation Vesicle-mediated Transport Positive Regulation Of Polarized Epithelial Cell Differentiation Hindbrain Development Cellular Protein Localization Cloaca Development Photoreceptor Cell Outer Segment Organization Pronephric Nephron Tubule Morphogenesis Pronephric Duct Morphogenesis Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Behavior Cilium Assembly Specification Of Axis Polarity Kupffer's Vesicle Development Left/right Axis Specification Otic Vesicle Development
Pathways		PTK6 Regulates Proteins Involved in RNA Processing	Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Arthritis (juvenile idiopathic) ( 33106285) Asthma ( 34103634 32296059) Basophil percentage of white cells ( 32888494) Granulocyte count ( 27863252) Hodgkin's lymphoma ( 29196614) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 24076602 21833088) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Nodular sclerosis Hodgkin lymphoma ( 29196614) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Selective IgA deficiency ( 27723758) Serum omega-3 polyunsaturated fatty acid concentration in metabolic syndrome ( 31991592) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Systemic lupus erythematosus ( 27399966 26502338 28714469) White blood cell count ( 32888494 27863252)
Interacting Genes		114 interacting genes: ABI2 ACTB AGO1 AHI1 AMPH APBB1 ARHGEF4 ARHGEF9 AZIN1 BAIAP2L1 BTK CBL CD2AP CDC42 CDK1 CIRBP CLK1 CREB3L3 CREBBP CRK CRKL CSK DDX5 DHX9 DLG1 DLG2 DLG3 DLG4 DNMBP DOCK2 DOCK3 EFEMP1 EMG1 FGR FNBP4 FRK FXR1 FXR2 FYN GAS7 GPHN GRAP GRAP2 GRB2 HCK HNRNPK INSR ITK ITPRID2 ITSN1 ITSN2 JAK3 KHDRBS3 LCK LYN MAPK1 MYO1C MYO7A NCF1 NCK1 NCK2 NCKIPSD NPHP1 OGT OSTF1 PACSIN1 PALS2 PIK3R1 PIK3R3 PLCG1 PLCG2 POT1 PPP1R13B PRMT1 PSTPIP1 PTBP2 PTK6 PTPN6 RALY RAPSN RASA1 RBFOX2 RBM7 RBMX RUSC2 SASH1 SCG5 SH3PXD2A SH3YL1 SHANK3 SKAP2 SMAD2 SMARCA2 SNX30 SNX9 SORBS1 SPATA13 SRC SRPK2 STAT3 STUB1 TBL1X TJP1 TSPOAP1 TUBB3 UBA52 UBASH3B UBC VAV1 WBP4 YES1 YTHDC1 ZBTB7A ZDHHC6	3 interacting genes: ARFGEF3 IFNGR1 KHDRBS1
Entrez ID		10657	54806
HPRD ID		03926	10597
Ensembl ID		ENSG00000121774	ENSG00000135541
Uniprot IDs		Q07666	Q8N157 Q8NER0
PDB IDs		2XA6 3QHE	4ESR
Enriched GO Terms of Interacting Partners?
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