CCT7 and NHLH1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CCT7	NHLH1
Description		chaperonin containing TCP1 subunit 7	nescient helix-loop-helix 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Chaperonin-containing T-complex Microtubule Cell Body Extracellular Exosome	Chromatin Nucleus
	Molecular Function	Protein Binding ATP Binding Protein Folding Chaperone Unfolded Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Protein Folding Binding Of Sperm To Zona Pellucida Positive Regulation Of Telomere Maintenance Via Telomerase Protein Stabilization Toxin Transport Positive Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body	Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding RHOBTB2 GTPase cycle RHOBTB1 GTPase cycle
Drugs
Diseases
GWAS		General cognitive ability ( 29844566)
Interacting Genes		23 interacting genes: ANXA1 ANXA7 APP ATP5F1C CDKN1A CEBPE CRMP1 DNM2 EEF1G KAT5 KRAS LINC01554 MED31 NHLH1 NKX3-1 OGT PRPF40A RAP1B RCC1 SUMO4 TCP1 WBP2 ZNRD2	11 interacting genes: CCT7 CENPP CSRP3 HIVEP1 INO80E LMO1 LMO2 LMO4 PIM1 PSME2 TCF3
Entrez ID		10574	4807
HPRD ID		06896	01212
Ensembl ID		ENSG00000135624	ENSG00000171786
Uniprot IDs		Q99832	Q02575 Q5T203
PDB IDs		6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8 7LUM 7LUP
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
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