NHLH1 and CENPP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		NHLH1	CENPP
Description		nescient helix-loop-helix 1	centromere protein P
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Chromosome, Centromeric Region Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	CENP-A Containing Nucleosome Assembly
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Blood protein levels ( 29875488) End-stage renal disease ( 29885931) HDL cholesterol levels ( 32203549) Height ( 28552196 31562340) Malaria ( 31844061) Pulse pressure ( 30578418) Systolic blood pressure ( 30224653 30578418) Triglyceride levels ( 32203549) Urate levels ( 31578528) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		11 interacting genes: CCT7 CENPP CSRP3 HIVEP1 INO80E LMO1 LMO2 LMO4 PIM1 PSME2 TCF3	27 interacting genes: ATP6V0D2 BACH2 C2orf88 CCDC33 CCDC85B CENPO CEP44 GOLGA2 HAUS1 KIAA1328 KLC3 LMNA MBD3 NHLH1 NTAQ1 PKNOX2 POLR3K RNF126 RPIA SERTAD3 STXBP1 SYCE1L TEX11 TOX2 USHBP1 ZNF341 ZNF765
Entrez ID		4807	401541
HPRD ID		01212	17989
Ensembl ID		ENSG00000171786	ENSG00000188312
Uniprot IDs		Q02575 Q5T203	Q6IPU0 Q7Z672
PDB IDs
Enriched GO Terms of Interacting Partners?
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