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CCT7 and ANXA1
Number of citations of the paper that reports this interaction (PubMedID
21900206
)
136
Data Source:
BioGRID
(two hybrid)
CCT7
ANXA1
Description
chaperonin containing TCP1 subunit 7
annexin A1
Image
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Chaperonin-containing T-complex
Microtubule
Cell Body
Extracellular Exosome
Cornified Envelope
Phagocytic Cup
Extracellular Region
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Endosome
Cytosol
Actin Filament
Plasma Membrane
Adherens Junction
Focal Adhesion
Cell Surface
Basolateral Plasma Membrane
Apical Plasma Membrane
Lateral Plasma Membrane
Extrinsic Component Of Membrane
Extrinsic Component Of External Side Of Plasma Membrane
Extrinsic Component Of Endosome Membrane
Motile Cilium
Early Endosome Membrane
Mitochondrial Membrane
Vesicle
Protein-containing Complex
Sarcolemma
Mast Cell Granule
Collagen-containing Extracellular Matrix
Extracellular Exosome
Synaptic Membrane
Molecular Function
Protein Binding
ATP Binding
Protein Folding Chaperone
Unfolded Protein Binding
Single-stranded DNA Binding
Single-stranded RNA Binding
Signaling Receptor Binding
Calcium Ion Binding
Protein Binding
Phospholipid Binding
Calcium-dependent Phospholipid Binding
Phospholipase A2 Inhibitor Activity
Double-stranded DNA Helicase Activity
Identical Protein Binding
Calcium-dependent Protein Binding
Cadherin Binding Involved In Cell-cell Adhesion
DNA/DNA Annealing Activity
Biological Process
Protein Folding
Binding Of Sperm To Zona Pellucida
Positive Regulation Of Telomere Maintenance Via Telomerase
Protein Stabilization
Toxin Transport
Positive Regulation Of Establishment Of Protein Localization To Telomere
Positive Regulation Of Protein Localization To Cajal Body
Positive Regulation Of Telomerase RNA Localization To Cajal Body
Neutrophil Homeostasis
Adaptive Immune Response
Monocyte Chemotaxis
Regulation Of Leukocyte Migration
Phagocytosis
Inflammatory Response
Signal Transduction
Cell Surface Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Regulation Of Cell Shape
Response To Xenobiotic Stimulus
Response To X-ray
Myoblast Migration Involved In Skeletal Muscle Regeneration
Peptide Cross-linking
Insulin Secretion
Keratinocyte Differentiation
Prostate Gland Development
Endocrine Pancreas Development
Positive Regulation Of Vesicle Fusion
Positive Regulation Of Prostaglandin Biosynthetic Process
Actin Cytoskeleton Reorganization
Response To Estradiol
DNA Duplex Unwinding
Regulation Of Interleukin-1 Production
Negative Regulation Of Interleukin-8 Production
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Neutrophil Apoptotic Process
Cellular Response To Vascular Endothelial Growth Factor Stimulus
Gliogenesis
Positive Regulation Of T Cell Proliferation
Negative Regulation Of Apoptotic Process
Response To Peptide Hormone
Estrous Cycle
Innate Immune Response
Positive Regulation Of T-helper 1 Cell Differentiation
Negative Regulation Of T-helper 2 Cell Differentiation
Negative Regulation Of Exocytosis
Alpha-beta T Cell Differentiation
Regulation Of Hormone Secretion
Arachidonic Acid Secretion
Negative Regulation Of Protein Secretion
Regulation Of Inflammatory Response
Cellular Response To Hydrogen Peroxide
Hepatocyte Differentiation
Prolactin Secretion
Response To Interleukin-1
Cellular Response To Glucocorticoid Stimulus
Granulocyte Chemotaxis
Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Positive Regulation Of Wound Healing
Neutrophil Clearance
Cell-cell Adhesion
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Phospholipase A2 Activity
Pathways
Prefoldin mediated transfer of substrate to CCT/TriC
Formation of tubulin folding intermediates by CCT/TriC
Folding of actin by CCT/TriC
Association of TriC/CCT with target proteins during biosynthesis
Association of TriC/CCT with target proteins during biosynthesis
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
RHOBTB2 GTPase cycle
RHOBTB1 GTPase cycle
G alpha (q) signalling events
G alpha (i) signalling events
Formyl peptide receptors bind formyl peptides and many other ligands
Smooth Muscle Contraction
Interleukin-4 and Interleukin-13 signaling
Drugs
Amcinonide
Fluocinolone acetonide
Hydrocortisone
Methylprednisolone
Clobetasol propionate
Budesonide
Dexamethasone
Hydrocortisone aceponate
Hydrocortisone acetate
Hydrocortisone butyrate
Hydrocortisone cypionate
Hydrocortisone phosphate
Hydrocortisone probutate
Hydrocortisone valerate
Prednisolone phosphate
Dexamethasone acetate
Betamethasone phosphate
Diseases
GWAS
General cognitive ability (
29844566
)
Blood protein levels (
28240269
)
Chronotype (
30696823
)
Cortical surface area (
32963231
)
Cortical volume (
32963231
)
Metabolite levels (
23823483
)
Parkinson's disease (
26227905
)
Schizophrenia, bipolar disorder and depression (combined) (
20713499
)
Urate levels in obese individuals (
25811787
)
Interacting Genes
23 interacting genes:
ANXA1
ANXA7
APP
ATP5F1C
CDKN1A
CEBPE
CRMP1
DNM2
EEF1G
KAT5
KRAS
LINC01554
MED31
NHLH1
NKX3-1
OGT
PRPF40A
RAP1B
RCC1
SUMO4
TCP1
WBP2
ZNRD2
35 interacting genes:
APBB1
CCT7
COPS6
CSAD
CZIB
DYSF
EGFR
EPHA2
ERG28
FAF1
FPR1
GAPDH
HMGA1
HSPB1
KLHL23
KMT2B
KRT8
LNPK
LRIF1
MEIS2
OTUB1
PRKCI
RPA1
S100A11
SRC
SUMO2
TGM2
TRPM7
UBE2D1
UBE2I
UBE3A
UCHL5
UNC119
USP7
YWHAQ
Entrez ID
10574
301
HPRD ID
06896
01060
Ensembl ID
ENSG00000135624
ENSG00000135046
Uniprot IDs
Q99832
P04083
Q5TZZ9
PDB IDs
6NR8
6NR9
6NRA
6NRB
6NRC
6NRD
6QB8
7LUM
7LUP
1AIN
1BO9
1QLS
5VFW
Enriched GO Terms of Interacting Partners
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