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OLFM4 and CLEC7A
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
86
Data Source:
BioGRID
(two hybrid)
OLFM4
CLEC7A
Description
olfactomedin 4
C-type lectin domain containing 7A
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Nucleoplasm
Mitochondrion
Cytosol
Plasma Membrane
Secretory Granule
Protein-containing Complex
Specific Granule Lumen
Specific Granule
Azurophil Granule
Intercellular Bridge
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Tertiary Granule Lumen
Cytoplasm
Plasma Membrane
Cell Surface
Integral Component Of Membrane
Molecular Function
Catalytic Activity
Structural Molecule Activity
Protein Binding
Cadherin Binding
(1->3)-beta-D-glucan Binding
Protein Binding
Carbohydrate Binding
Pattern Recognition Receptor Activity
MHC Protein Binding
Metal Ion Binding
Biological Process
Cell Adhesion
Regulation Of Necrotic Cell Death
Regulation Of Apoptotic Process
Regulation Of Phagocytosis
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Regulation Of Neutrophil Extravasation
Cell Activation
Response To Yeast
Detection Of Yeast
Stimulatory C-type Lectin Receptor Signaling Pathway
Leukocyte Activation Involved In Immune Response
Positive Regulation Of Dendritic Cell Cytokine Production
Phagocytosis, Recognition
Inflammatory Response
Cell Recognition
Positive Regulation Of Cell Population Proliferation
Carbohydrate Mediated Signaling
Positive Regulation Of Gene Expression
Detection Of Fungus
Positive Regulation Of Cell Migration
Positive Regulation Of Protein-containing Complex Assembly
Detection Of Molecule Of Fungal Origin
Positive Regulation Of Interferon-gamma Production
Positive Regulation Of Interleukin-1 Beta Production
Positive Regulation Of Interleukin-10 Production
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Interleukin-23 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Superoxide Anion Generation
T Cell Activation
Defense Response To Protozoan
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Nitric Oxide Biosynthetic Process
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Phagocytosis
Positive Regulation Of Calcium-mediated Signaling
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Lymphocyte Activation
Positive Regulation Of Killing Of Cells Of Other Organism
Positive Regulation Of Respiratory Burst
Antifungal Innate Immune Response
Regulation Of Calcineurin-NFAT Signaling Cascade
Cellular Response To Molecule Of Fungal Origin
Positive Regulation Of Monocyte Chemotactic Protein-1 Production
Positive Regulation Of Wound Healing
Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of Cell Maturation
Positive Regulation Of T-helper 17 Type Immune Response
Pathways
Neutrophil degranulation
CLEC7A (Dectin-1) signaling
CLEC7A (Dectin-1) signaling
Drugs
Diseases
GWAS
Adult body size (
32376654
)
Adventurousness (
30643258
)
Amyotrophic lateral sclerosis (sporadic) (
24529757
)
Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) (
31835028
)
BMI (adjusted for smoking behaviour) (
28443625
)
BMI in non-smokers (
28443625
)
Body mass index (
29381148
26961502
24861553
25673413
28448500
25953783
)
Body mass index (joint analysis main effects and physical activity interaction) (
28448500
)
Body mass index (joint analysis main effects and smoking interaction) (
28443625
)
Body size at age 10 (
32376654
)
Cerebrospinal P-tau181p levels (
28247064
)
Childhood body mass index (
26604143
)
Depression (
29700475
)
Hip circumference (
25673412
)
Immune response to anthrax vaccine (
22658931
)
Intelligence (MTAG) (
29326435
)
Major depressive disorder (
27479909
)
Multisite chronic pain (
33830993
)
Obesity (
23563607
22484627
)
Obesity-related traits (
23251661
)
Waist circumference (
25673412
)
Interacting Genes
37 interacting genes:
APP
AQP2
AQP3
BSCL2
C3
CLDN7
CLEC17A
CLEC7A
CLSTN3
CLTRN
CREB3L1
EREG
FAM209A
FNDC9
IL11RA
ITM2C
KASH5
KIR2DL3
KIR3DL3
LDLRAD1
LEUTX
LHFPL2
PCDH17
PRR20A
PRR20B
PVR
PVRIG
QPCTL
SLC18A1
SLC22A23
SUSD3
SYNE4
TFR2
TMEM130
TNFSF11
TNFSF14
TSPAN18
47 interacting genes:
ADAM33
AIP
ARL13B
ASGR2
BNIP3
BNIP3L
C14orf180
CALM3
CD53
CD74
CTXN3
CXCL9
FAM3A
FCGR1A
FNDC9
GJB1
HSPD1
IFNGR2
IL1RL1
JAGN1
KLRC1
KTN1
MTIF3
NEMP1
NINJ2
NSG2
OCLN
OLFM4
OPRM1
PTTG1IP
RANBP9
RHOU
SAR1A
SEC22A
SGCB
SMIM3
SPINT1
SUSD3
SYNE4
TEX29
TLCD4
TMEM79
TMPRSS2
TMPRSS4
UPK2
VSIR
ZFPL1
Entrez ID
10562
64581
HPRD ID
06580
08396
Ensembl ID
ENSG00000102837
ENSG00000172243
Uniprot IDs
A0A024QZ95
Q6UX06
A0A024RAN9
A0A0S2Z5Q1
Q68D78
Q9BXN2
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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