OLFM4 and LHFPL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		OLFM4	LHFPL2
Description		olfactomedin 4	LHFPL tetraspan subfamily member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleoplasm Mitochondrion Cytosol Plasma Membrane Secretory Granule Protein-containing Complex Specific Granule Lumen Specific Granule Azurophil Granule Intercellular Bridge Perinuclear Region Of Cytoplasm Extracellular Exosome Tertiary Granule Lumen	Cellular_component Plasma Membrane Membrane Integral Component Of Membrane Platelet Alpha Granule Membrane
	Molecular Function	Catalytic Activity Structural Molecule Activity Protein Binding Cadherin Binding	Molecular_function Protein Binding
	Biological Process	Cell Adhesion Regulation Of Necrotic Cell Death Regulation Of Apoptotic Process Regulation Of Phagocytosis Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Neutrophil Extravasation	Single Fertilization Biological_process Development Of Primary Female Sexual Characteristics Development Of Primary Male Sexual Characteristics Positive Regulation Of Fertilization
Pathways		Neutrophil degranulation	Platelet degranulation
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 29381148 26961502 24861553 25673413 28448500 25953783) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body size at age 10 ( 32376654) Cerebrospinal P-tau181p levels ( 28247064) Childhood body mass index ( 26604143) Depression ( 29700475) Hip circumference ( 25673412) Immune response to anthrax vaccine ( 22658931) Intelligence (MTAG) ( 29326435) Major depressive disorder ( 27479909) Multisite chronic pain ( 33830993) Obesity ( 23563607 22484627) Obesity-related traits ( 23251661) Waist circumference ( 25673412)	Birth weight ( 31043758) Blood and toenail selenium levels ( 25343990) Hippocampal atrophy ( 19668339) Macular thickness ( 30535121) Metabolite levels ( 23823483) Parkinson's disease (familial, age at onset) ( 27402877) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Pulse pressure ( 28135244 27841878 30578418) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		37 interacting genes: APP AQP2 AQP3 BSCL2 C3 CLDN7 CLEC17A CLEC7A CLSTN3 CLTRN CREB3L1 EREG FAM209A FNDC9 IL11RA ITM2C KASH5 KIR2DL3 KIR3DL3 LDLRAD1 LEUTX LHFPL2 PCDH17 PRR20A PRR20B PVR PVRIG QPCTL SLC18A1 SLC22A23 SUSD3 SYNE4 TFR2 TMEM130 TNFSF11 TNFSF14 TSPAN18	11 interacting genes: FXYD6 GAST GJA5 GJB1 GPR152 OLFM4 SCARF1 SNORC TBCA TMEM128 TMEM147
Entrez ID		10562	10184
HPRD ID		06580	17272
Ensembl ID		ENSG00000102837	ENSG00000145685
Uniprot IDs		A0A024QZ95 Q6UX06	A0A024RAM8 Q6ZUX7
PDB IDs
Enriched GO Terms of Interacting Partners?
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