UBD and OTUB1

Number of citations of the paper that reports this interaction (PubMedID 30718280)
6

Data Source:
BioGRID (pull down)

		UBD	OTUB1
Description		ubiquitin D	OTU deubiquitinase, ubiquitin aldehyde binding 1
Image
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cytosol Aggresome	Nucleus Nucleoplasm Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Proteasome Binding	Thiol-dependent Deubiquitinase Protein Binding NEDD8-specific Protease Activity Ubiquitin Protein Ligase Binding Ubiquitin Binding
	Biological Process	Proteolysis Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Response To Interferon-gamma Response To Tumor Necrosis Factor Myeloid Dendritic Cell Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Aggresome Assembly Regulation Of Mitotic Cell Cycle Phase Transition	Adaptive Immune Response DNA Repair Cellular Response To DNA Damage Stimulus Protein K48-linked Deubiquitination Cellular Response To Interleukin-1 Negative Regulation Of Histone H2A K63-linked Ubiquitination Negative Regulation Of Double-strand Break Repair
Pathways		Neddylation	Ub-specific processing proteases Ovarian tumor domain proteases
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Brain morphology (MOSTest) ( 32665545) Crohn's disease ( 22412388) Fish- and plant-related diet ( 32066663) Height ( 25429064) Hemoglobin levels ( 32327693) Refractive error ( 32231278) Serum alkaline phosphatase levels ( 33547301) Subcortical volume (MOSTest) ( 32665545)	Bipolar disorder ( 31043756)
Interacting Genes		14 interacting genes: MAD2L1 NUB1 OTUB1 PDE9A PSMD4 SAE1 SRPK1 SRPK2 TGFBR1 UBA2 UBA6 UBE2D2 UBE2Z USP16	58 interacting genes: ACVR1 ACVR1B ANXA1 ANXA7 AURKA BIRC2 BMPR1A BMPR1B CD274 CDKN1A CPEB2 CSNK2A1 ECT2 ESR1 FOXM1 H2AX IL1RL2 KDM1A MAPT NEDD8 PACS1 PJA1 RFFL RHOA RNF126 RNF128 SLC7A11 SMAD2 SMAD3 SMAD4 SMAD9 SNAI1 TGFBR1 TP53 TRAF6 TRIM54 TRIM55 TRIM63 TSC22D1 TTR UBA6 UBC UBD UBE2D1 UBE2D2 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2L3 UBE2N UBE2S UBE2V2 UBE2Z UBE4B USP15 USP21 USP28
Entrez ID		10537	55611
HPRD ID		09354	08493
Ensembl ID		ENSG00000213886	ENSG00000167770
Uniprot IDs		A0A1U9X8S6 O15205	B3KUV5 Q96FW1
PDB IDs		2MBE 6GF1 6GF2	2ZFY 3VON 4DDG 4DDI 4DHZ 4I6L 4LDT
Enriched GO Terms of Interacting Partners?
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